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Effect of theophylline and triiodothyronine on some early estrogenic responses in the rat uterus

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Summary

Theophylline increases and triodothyronine decreases uterine edema induced by physiological doses of estradiol-17β. Both of them decrease estrogen-induced uterine eosinophilia and the number of blood eosinophils, suggesting an explanation for the results in the uterus.

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Authors and Affiliations

  1. Department of Physiology and Biophysics and Laboratory of Experimental Endocrinology, Department of Experimental Morphology, University of Chile Medical School, Santiago Norte, Casilla 6524, Correo 7, Santiago, (Chile)

    J. Steinsapir, S. León, P. Bustón, M. Alburquerque, A. M. Rojas, A. Fernández, R. Pacheco & A. Tchernitchin

Authors
  1. J. Steinsapir
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  2. S. León
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  3. P. Bustón
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  4. M. Alburquerque
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  5. A. M. Rojas
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  6. A. Fernández
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  7. R. Pacheco
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  8. A. Tchernitchin
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Additional information

Acknowledgments.—We wish to thank Dr G. Pineda, Salvador Hospital, Santiago, for the gift of L-triiodothyronine (Sigma). This work was supported by grant B 012-783, Servicio de Desarrollo Científico y Creación Artística, University of Chile.

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Steinsapir, J., León, S., Bustón, P. et al. Effect of theophylline and triiodothyronine on some early estrogenic responses in the rat uterus. Experientia 35, 1472–1474 (1979). https://doi.org/10.1007/BF01962792

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  • DOI: https://doi.org/10.1007/BF01962792

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