Summary
In spontaneously hypertensive rats (SHRs) chronically treated during their growth with β-adrenoceptor blocking drugs, no correlation was found between the reduction in heart rate and the prevention of genetic hypertension development.
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References
L. Weiss, Y. Lundgren and B. Folkow, Acta physiol. scand.91, 447 (1974).
J.R. Boissier, J.F. Giudicelli and C. Richer, Nouv. Presse méd.4, 1661 (1975).
W.V. Judy, A.M. Watanabe, D.P. Henry, H.B. Beach, W.R. Murphy and G.M. Hockel, Circulation Res.38 (suppl. II), 21 (1976).
B. Basil, R.F. Collins and M.F. Cuthbert, Br. J. Pharmac.47, 620 P (1973).
C. Richer, J.R. Boissier and J.F. Giudicelli, Eur. J. Pharmac.47, 393 (1978).
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This work was supported by a grant from the Scientific Council of the Faculté de Médecine Paris-Sud (1978/754).
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Richer, C., Venturini-Souto, N. & Giudicelli, J.F. β-Adrenoceptor blocking drugs, heart rate and genetic hypertension development in rats. Experientia 35, 656–657 (1979). https://doi.org/10.1007/BF01960381
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DOI: https://doi.org/10.1007/BF01960381