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Inhibitory effect of cytokinins on PHA-induced human lymphocyte stimulation

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Summary

The inhibitory effect of various purine derivatives on PHA-induced human lymphocyte blast formation was studied. Two nucleoside cytokinins, N6-benzyladenosine and N6-isopentenyladenosine, inhibited blast formation at concentrations as low as 10−6 M. However, the other cytokinins, which lacked the ribosyl residue at N9 position, had to be at the higher molar concentration of 10−4 before they could induce the same inhibitory effect.

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Authors and Affiliations

  1. Department of Bacteriology, Tohoku University School of Medicine, 2-1 Seiryo-machi, Sendai, Japan

    T. Saito, Y. Shibata, T. Kurokawa & N. Ishida

Authors
  1. T. Saito
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  2. Y. Shibata
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  3. T. Kurokawa
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  4. N. Ishida
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Saito, T., Shibata, Y., Kurokawa, T. et al. Inhibitory effect of cytokinins on PHA-induced human lymphocyte stimulation. Experientia 35, 685–686 (1979). https://doi.org/10.1007/BF01960399

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  • DOI: https://doi.org/10.1007/BF01960399

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