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Effect of 3-methylcholanthrene on RNA polymerase and protein kinase activities of transcriptionally active chromatin subfraction in rat liver

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Summary

The activities of RNA polymerases and nuclear protein kinases were determined in subfractions of rat liver nuclei after a single dose of the polycyclic aromatic hydrocarbon 3-methylcholanthrene (3-MC). Both enzyme activities as well as the in vivo phosphorylation of chromatin proteins were enhanced by 3-MC in the transcriptionally active subfraction of chromatin.

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Author notes

  1. U. Kleeberg

    Present address: Institute of Pharmacology and Toxicology, Friedrich Schiller University, Jena, Germany

Authors and Affiliations

  1. Department of Biology, University Medical School, Pécs, Hungary

    J. Szeberényi, U. Kleeberg & A. Tigyi

Authors
  1. J. Szeberényi
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  2. U. Kleeberg
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  3. A. Tigyi
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Szeberényi, J., Kleeberg, U. & Tigyi, A. Effect of 3-methylcholanthrene on RNA polymerase and protein kinase activities of transcriptionally active chromatin subfraction in rat liver. Experientia 38, 687–689 (1982). https://doi.org/10.1007/BF01964097

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  • DOI: https://doi.org/10.1007/BF01964097

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