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Changes in brush-border enzyme activities of intestinal epithelial cells isolated from the villus-crypt axis during the early phase of alloxan diabetes in rats

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Summary

The sucrase activity in enterocytes isolated from the villus crypt axis was found to increase in all regions of the villus from day 2 after induction of diabetes, and the increase continued until day 4. In contrast, alkaline phosphatase activity increased mainly in the apical one-third of the villus-crypt column, and the increase occurred abruptly on day 4 with increase in food intake.

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Authors and Affiliations

  1. Department of Nutrition, School of Medicine, The University of Tokushima, 770, Tokushima, Japan

    Y. Nakabou, K. Ikeuchi, H. Minami & H. Hagihira

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  1. Y. Nakabou
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  2. K. Ikeuchi
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  3. H. Minami
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  4. H. Hagihira
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Nakabou, Y., Ikeuchi, K., Minami, H. et al. Changes in brush-border enzyme activities of intestinal epithelial cells isolated from the villus-crypt axis during the early phase of alloxan diabetes in rats. Experientia 41, 482–484 (1985). https://doi.org/10.1007/BF01966159

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  • DOI: https://doi.org/10.1007/BF01966159

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