Summary
The principle of ‘central volume’ is applied to the sodium and water contents of the inner medulla of the mammalian kidney. The analysis raises questions about the possibility of concentrating sodium ions in the inner medulla by a mechanism that postulates, in the same tissue segment, water withdrawal from the descending thin limb of the loop of Henle and sodium entry from the ascending thin limb.
References
Kuhn, W., and Ryffel, K., Hoppe-Seilers Z. physiol. Chem.276 (1942) 145.
Hargitay, B., and Kuhn, W., Z. Elektrochem.55 (1951) 539.
Kuhn, W., and Ramel, A., Helv. chim. Acta42 (1959) 628.
Kiil, F., and Aukland, K., J. clin. Lab. Invest.12 (1960) 290.
Stephenson, J. L., Kidney Int.2 (1972) 85.
Kokko, J. P., and Rector, F. C., Kidney Int.2 (1972) 214.
Stephenson, J. K., Rev. Biophys. Bioeng.7 (1978) 315.
Schmidt-Nielsen, B., Graves, B., and Roth, J., Am. J. Physiol.244 (1983) F472.
Morel, F. F., Guinnebault, M., and Amiel, C., Helv. physiol. pharmac. Acta18 (1960) 183.
Morel, F. F., and Guinnebault, M., J. Physiol. Paris53 (1961) 75.
White, H. L., Rolf, D., and Tosteson, D. C., Am. J. Physiol.200 (1961) 591.
Pennell, J. P., Sanjana, V., Frey, N. R., and Jamison, R. L., J. Clin. Invest.55 (1975) 399.
Drost-Hansen, W., The occurrence and extent of vicinal water, in: Biophysics of Water, p. 163. Ed. F. Franks, Wiley & Sons, New York 1982.
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Pinter, G.G., Wilson, P.D. On the renal inner medullary concentration of sodium. Experientia 42, 1010–1012 (1986). https://doi.org/10.1007/BF01940709
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DOI: https://doi.org/10.1007/BF01940709