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Effects of blood sampling, anesthesia and surgery on plasma vasopressin concentration in rats

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Abstract

The influence of blood sampling, anesthesia and surgery on plasma vasopressin concentration was assessed in rats. Mean plasma concentration in conscious, chronically catheterized rats was 1.4±0.1 pg/ml (n=6). This value remained constant over repeated plasma samplings in the same animals. On the other hand, decapitation increased the plasma vasopressin concentration to 6.0±2.4 (in pg/ml) (n=6), inactin anesthesia to 2.9±0.6 (n=6), anesthesia and femoral cannulation to 13.3±5.8 (n=6) and surgery for renal micropuncture to 81.3±35.0 (n=6). It is concluded that the level of circulating plasma vasopressin is highly dependent on the sampling technique and is closely related to the extent of surgery.

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Literatur

  1. Maddox, D. A., Price, D. C., and Rector, F. C., Am. J. Physiol.2(6) (1977) F600.

    Google Scholar 

  2. Corman, B., and Michel, J. B., Am. J. Physiol.253 (1987) R555.

    Article  CAS  PubMed  Google Scholar 

  3. Corman, B., and Roinel, N., Am. J. Physiol.260 (1991) F75.

    CAS  PubMed  Google Scholar 

  4. Skowsky, W. R., Rosembloom, A. R., and Fisher, D. A., J. clin. Endocr. Metab.38 (1974) 278.

    Article  CAS  PubMed  Google Scholar 

  5. Keil, L. C., and Sever, W. R., Endocrinology100 (1977) 30.

    Article  CAS  PubMed  Google Scholar 

  6. Cowley, A. W., in: Cardiovascular Physiology, vol. 4: International Review of Physiology, vol. 26, pp. 189–242. Eds A. C. Cuyton and J. E. Hall. University Park Press, Baltimore 1982.

    Google Scholar 

  7. Brunner, D. B., Burnier, M., and Brunner, H. R., Am. J. Physiol.244 (1983) H259.

    Article  CAS  PubMed  Google Scholar 

  8. Husain, M. K., Manger, W. M., Rock, T. W., Weiss, R. J., and Frantz, A. G., Endocrinology104 (1979) 641.

    Article  CAS  PubMed  Google Scholar 

  9. Cowley, A. W., and Liard, J. F., in: Vasopressin, Principles and Properties, pp. 389–433. Eds D. M. Gash and G. J. Boer. Plenum Press, New York 1987.

    Chapter  Google Scholar 

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Authors and Affiliations

  1. Service de Biologie Cellulaire, Département de Biologie Cellulaire et Moléculaire, CEN Saclay, F-91 191, Gif-sur-Yvette

    B. Corman

  2. Laboratoire de Physiologie de l'Environnement, Faculté de Médecine Grange-Blanche, 8 av. Rockefeller, F-69 373, Lyon, France

    G. Geelen

Authors
  1. B. Corman
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  2. G. Geelen
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Corman, B., Geelen, G. Effects of blood sampling, anesthesia and surgery on plasma vasopressin concentration in rats. Experientia 48, 268–270 (1992). https://doi.org/10.1007/BF01930472

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  • DOI: https://doi.org/10.1007/BF01930472

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