Abstract
The effect of the concentration of benzoyl peroxide in poly(methyl methacrylate) bone cement formulations on their setting characteristics, particularly peak temperature and setting time, were studied. An optimization of the concentration of benzoyl peroxide was made with respect to curing parameters and compared with the residual monomer content. The mechanical properties of the different formulations were also determined and the results indicated that a composition of 1.5% wt/wt and 0.82% wt/wt of benzoyl peroxide and N,N-dimethyl-p-toluidine concentrations, respectively, gave the highest yield strength. Studies on the preparation of bone cement formulations containing different amounts of barium sulphate were also performed to assess the effect on the polymerization process and mechanical properties of the cements.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
S. SAHA and S. PAL, J. Biomed. Mater. Res. 18 (1984) 435—462.
E. P. LAUTENSCHLAGER, S. I. STUPP and J. C. KELLER, in “Functional behaviour of orthopaedic biomaterial. Vol. II. Applications”, edited by P.Ducheyne and G. W. Hastings (CRC Press, Boca Raton, CA, 1987) pp. 87—119.
J. R. WIJN, T. J. J. H. SLOOFF and F. C. M. DRIESSENS, Acta Orthop. Scand. 46 (1975) 38—51.
S. S. HAAS, G. M. BRAUER, G. DICKSON and N. A. WASHINGTON, J. Bone Jt Surg. 57-A (1975) 380—391.
P. C. NOBLE, Biomaterials 4 (1983) 94—99.
C. MIGLIARESI, L. FAMBRI and J. KOLARIK, ibid. 15 (1994) 875—881.
D. W. BURKE, E. I. GATES and W. H. HARRIS, J. Bone Jt Surg. 66-A (1984) 1265—1273.
R. L. WIXON, E. P. LAUTENSCHLAGER and M. A. NOVAK, J. Arthroplasty 2 (1987) 141.
J. CHARNLEY, Acrylic cement in orthopaedic surgery (Williams and Wilkins, Baltimore, 1970).
W. L. JAFFEE, R. M. ROSE and E. L. RADIN, J. Bone Jt Surg. 56 (1974) 1711—1714.
S. C. BAYNE, E. P. LAUTENSCHLAGER, E. H. GREENER and P. R. MEYER, J. Biomed. Mater. Res. 11 (1977) 859.
C. M. SCHOENFELD, G. J. CONRAD and E. P. LAUTENSCHLAGER, ibid. 13 (1979) 135—147.
P. W. R. BEAUMONT, J. Biomed. Engng 1 (1979) 147—152.
B. PASCUAL, B. VAZQUEZ, I. GONI, M. GURRUCHAGA, M. P. GINEBRA, F. J. GIL, J. A. PLANELL, B. LEVENFELD and J. SAN ROMAN, Biomaterials 17 (1996) 509—16.
A. MURAKAMI, J. C. BEHIRI and W. BONFIELD, J.Mater. Sci. 23 (1988) 2029—2036.
C. D. JEFFRISS, A. J. C. LEE and R. S. M. LING, J. Biomed. Joint Surg. 57B (1975) 511—518.
E. B. SHEININ, W. R. BENSON and W. L. BRANNON, J. Pharmaceutical Sci. 65 (1976) 280.
A. CASTALDINI, A. CAVALLINI, A. MORONI and R. OLMI, in “Biomaterials and biomechanics”, edited by P. Ducheyne, G. van der Perre and A. E. Aubert (Elsevier Science Publishers, Amsterdam, 1984).
A. SOGAL and S. F. HULBERT, Bioceramics 5 (1992) 213—224.
J. RUDIGIER, P. KIRSCHNER, I. E. RICHTER and C.H. SCHWEIKERT, in “Mechanical properties of biomaterials”, edited by G. W. Hastings and D. F. Williams (John Wiley and Sons, Chichester, UK), 1980).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
VAZQUEZ , B., DEB , S. & BONFIELD , W. Optimization of benzoyl peroxide concentration in an experimental bone cement based on poly(methyl methacrylate). Journal of Materials Science: Materials in Medicine 8, 455–460 (1997). https://doi.org/10.1023/A:1018565807727
Issue Date:
DOI: https://doi.org/10.1023/A:1018565807727