Skip to main content
SpringerLink
Log in

Crystal structures of bis(quinidinium) molybdate hydrate and quinidinium chloride hydrate: The question of the stable conformation of quinidine

  • Physical Chemistry
  • Structure And Physicochemical Properties Of Molecules
  • Published:
Bulletin of the Russian Academy of Sciences, Division of chemical science Aims and scope

Abstract

Anx-ray structural study of [QndH+]2[MoO 2−4 ]H2O (1) and [QndH+]Cl−H2O (2), where Qnd = quinidine, was conducted. The structures have an ionic structure, and the ions are joined by hydrogen bonds into chains (1) and layers (2). Quinidinium cations protonated at the quinuclidine N atom have a conformation with agauche position of the N atom and OH group (as in neutral quinidine) corresponding to the local, and not the global, minimum of the calculated conformational energy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature cited

  1. K. Van Dyke, C. Szustkiewicz, C. H. Lantz, and L. H. Saxe,Biochem. Pharmacol.,18, No. 1, 147 (1969).

    Google Scholar 

  2. C. C. Cheng,J. Pharm. Sci.,60, No. 4, 1596 (1971).

    PubMed  Google Scholar 

  3. B. J. Oleksyn and L. J. Lebioda,Polish J. Chem.,54, No. 4, 755 (1980).

    Google Scholar 

  4. S. Kashino and M. Haisa,Acta Crystallogr.,C39, No. 1, 310 (1983).

    Google Scholar 

  5. H. Ohbo, H. Okazaki, K. Miyoshi, and H. Yoneda,Bull. Chem. Soc. Jpn.,56, No. 7, 1982 (1983).

    Google Scholar 

  6. O. L. Carter, A. T. McPhail, and G. A.Sim, J. Chem. Soc. (A), No. 3, 365 (1967).

  7. R. Doherty, W. R. Benson, M. Maienthal, and J. McD. Stewart,J. Pharm. Sci.,67, No. 5, 1698 (1978).

    PubMed  Google Scholar 

  8. I. L. Karle and J. Karle,Proc. Nat. Acad. Sci. U.S.A.,78, 5938 (1981).

    Google Scholar 

  9. A. G. Orpen, L. Brammer, F. H. Allen, O. Kennard, D. G. Watson, and R. Taylor,J. Chem. Soc. Dalton Trans., No. 12, S1 (1989).

  10. W. Hamilton,Acta Crystallogr.,18, No. 2, 502 (1965).

    Google Scholar 

Download references

Authors
  1. É. B. Shamuratov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. S. Batsanov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yu. T. Struchkov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. N. Yunuskhodzhaev
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

A. N. Nesmeyanov Institute of Organoelemental Compounds, Russian Academy of Sciences, 117813 Moscow. Translated from Izvestiya Akademii Nauk, Seriya Khimicheskaya, No. 5, pp. 1073–1078, May, 1992.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shamuratov, É.B., Batsanov, A.S., Struchkov, Y.T. et al. Crystal structures of bis(quinidinium) molybdate hydrate and quinidinium chloride hydrate: The question of the stable conformation of quinidine. Russ Chem Bull 41, 841–845 (1992). https://doi.org/10.1007/BF00864530

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00864530

Keywords

Search

Navigation