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Phylogenetic relationships ofCryptococcus neoformans and some related basidiomycetous yeasts determined from partial large subunit rRNA sequences

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Abstract

The genusCryptococcus was found to be heterogeneous on the basis of partial rRNA sequences. The human-pathogenic speciesC. neoformans, comprising 4 serotypes and havingFilobasidiella neoformans andF. bacillispora as teleomorphs, was found at a relatively large distance fromFilobasidium. Serotypes B and C had identical sequences, while in A and D they were different, with D closer to B and C than to A.Filobasidiella depauperata, which lacks a yeast-like anamorph, clustered withF. neoformans.

The genusFilobasidium was clearly separated fromFilobasidiella and clustered withC. albidus, C. kuetzingii, C. gastricus, C. lupi, C. vishniaciae, C. bhutanensis, C. aerius, C. terreus andC. ater. The latter may represent the anamorph ofFilobasidium elegans. The organe to red species ofCryptococcus, as well asC. aquaticus andC. yarrowii, were found completely unrelated with these taxa,C. macerans being affiliated toCystofilobasidium capitatum.

The genusTrichosporon was found relatively homogeneous; it includesC. humicola, C. curvatus and the filamentous speciesHyalodendron lignicola. Cryptococcus flavus andC. dimennae probably belong to the Tremellales, though distances between these species are large. The positions ofC. laurentii andC. luteolus remains to be determined.

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Authors and Affiliations

  1. Unité de Mycologie, Institut Pasteur, 25, rue du Dr. Roux, 75724, Paris Cedex 15, France

    E. Guého & L. Improvisi

  2. Unité de Biologie Cellulaire Marine, URA 671-CNRS Paris 6, Station Zoologique 06230, Villefranche sur Mer, France

    R. Christen

  3. Centraalbureau voor Schimmelcultures, P.O. Box 273, 3740 AG, Baarn, The Netherlands

    G. S. de Hoog

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  1. E. Guého
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  4. G. S. de Hoog
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Guého, E., Improvisi, L., Christen, R. et al. Phylogenetic relationships ofCryptococcus neoformans and some related basidiomycetous yeasts determined from partial large subunit rRNA sequences. Antonie van Leeuwenhoek 63, 175–189 (1993). https://doi.org/10.1007/BF00872392

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