Abstract
Capsaicin was hydrolysed by lipase B from Candida antarctica into vanillylamine and 8-methyl-6-trans-nonenoic acid. Conversions of 70% were obtained after 72 h at 70 °C in water but decreased to only 15% when capsaicin was solubilized in 15% (v/v) ethanol/water after 72 h at 45 °C. No activity occurred in chloroform/water mixtures. According to our knowledge, this is the first report concerning amide hydrolysis by a lipase.
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Duarte, D.R., Castillo, E., Bárzana, E. et al. Capsaicin hydrolysis by Candida antarctica lipase. Biotechnology Letters 22, 1811–1814 (2000). https://doi.org/10.1023/A:1005622704504
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DOI: https://doi.org/10.1023/A:1005622704504