Skip to main content
SpringerLink
Log in

The effect of CO on growth and product formation in batch cultures ofClostridium acetobutylicum

  • Published:
Biotechnology Letters Aims and scope Submit manuscript

Summary

Carbon monoxide sparged in batch fermentations ofC. acetobutylicum inhibits the production of H2 by the hydrogenase and enhances the production of solvents by making available larger amounts of NAD(P)H2 to the cells. CO also inhibits biomass growth and acid formation. Its effect is most pronounced under fermentation conditions of excess carbon- and nitrogen-source supply.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Gray, C.T. and Gest, H. (1965).Science 148, 186–192.

    Google Scholar 

  • Kim, B.H., Bellows, P., Datta, R. and Zeikus, J.G. (1984).Appl. Environ. Microbiol. 48, 764–770.

    Google Scholar 

  • McLaughlin, J.K. (1984). M.S. thesis, Rice Univ., Houston, TX (USA).

  • Mortenson, L.E. and Chen, J.-S. (1975). In:Microbial Production and Utilization of Gases, H.G. Schlegel, G. Gottschalk and N. Pfennig, eds., pp. 69–74, Gottingen: E. Goltze, KG.

    Google Scholar 

  • Papoutsakis, E.T. (1983). In:The Acetone-Butanol Fermentation and Related Topics, J.D. Bu'lock and A.J. Bu'lock, eds., pp. 121–128, New (Surrey, UK): Science and Technology Letters.

    Google Scholar 

  • Papoutsakis, E.T. (1984).Biotechnol. Bioeng. 26, 174–187.

    Google Scholar 

  • Roos, J.W. (1984). M.S. thesis, Rice Univ., Houston, TX (USA).

  • Roos, J.W., McLaughlin, J.K. and Papoutsakis, E.T. (1985).Biotechnol. Bioeng., in press.

Download references

Author information

Authors and Affiliations

  1. Department of Chemical Engineering, Rice University, P.O. Box 1892, 77251, Houston, Texas, USA

    C. L. Meyer, J. K. McLaughlin & E. T. Papoutsakis

Authors
  1. C. L. Meyer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. K. McLaughlin
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. T. Papoutsakis
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Meyer, C.L., McLaughlin, J.K. & Papoutsakis, E.T. The effect of CO on growth and product formation in batch cultures ofClostridium acetobutylicum . Biotechnol Lett 7, 37–42 (1985). https://doi.org/10.1007/BF01032417

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01032417

Keywords

Search

Navigation