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Tibia metastasis without Prostate Specific Antigen (PSA) increase following radical vesiculo-prostatectomy

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Abstract

Objectives: PSA is regarded as the best method in the follow-up ofprostate carcinoma. After radical vesiculo-prostatectomy the prostatecarcinoma seldom recurs at zero or nearly zero PSA levels. Methods:The authors have used PSA since 1989 and they have found only one casewhere metastasis in the tibia came without an increase in PSA levels. Results: Tibia metastasis showed lower tissue activity of PSA than did theprimary tumor in the prostate. The authors think this explains the zero PSAlevel when the metastasis developed. Conclusions: The authors thinkbased on their case that PSA free progression prostate cacncers may caseswhere the metastases do not produce PSA.

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Authors and Affiliations

  1. Department of Urology, University Medical School, Pécs, Hungary

    J. Hübler

  2. Department of Pathology, University Medical School, Pécs, Hungary

    F. Sükösd

  3. Departments of Orthopedic Surgery, University Medical School, Pécs, Hungary

    M. Czipri

Authors
  1. J. Hübler
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  2. F. Sükösd
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  3. M. Czipri
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Hübler, J., Sükösd, F. & Czipri, M. Tibia metastasis without Prostate Specific Antigen (PSA) increase following radical vesiculo-prostatectomy. Int Urol Nephrol 32, 281–284 (2000). https://doi.org/10.1023/A:1007142910479

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  • DOI: https://doi.org/10.1023/A:1007142910479

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