Abstract
Ureteral reflux in female patients who also have latent uninhibited neurogenic bladder occurs synchronously with uninhibited contraction, is blocked by buscopan and is aggravated by besacholine. Intrinsic neuromuscular antireflux mechanism of the vesicoureteral junction (VUJ) appears to be affected by unknown ways with uninhibited contraction. Urethrovesical reflux observed synchronously with uninhibited contraction seems to play an additional role in the genesis of urinary infection. A different look is required in the management of these refluxes, in that concomitant use of the anticholinergic drugs is recommended in addition to the conventional approach for the control of infection, reflux and voiding symptoms.
Similar content being viewed by others
References
Lapides, J., Diokno, A. C.: Persistence of the infant bladder as a cause for urinary infection in girls.J. Urol., 100, 445 (1968).
Koyanagi, T., Ishikawa, I.: The study on recurrent urinary tract infection among female subjects. Etiological explanation from the functional study of the lower urinary tract.Jap. J. Urol., 64, 67 (1973).
Lapides, J.: Cystometry.JAMA, 201, 618 (1967).
Lyon, R. P., Marshall, S., Tanagho, E.: The ureteral orifice: Its configuration and competency.J. Urol., 102, 504 (1969).
Tanagho, E. A., Hutch, J. A., Meyers, F. H., Rambo, O. N., Jr.: Primary vesicoureteral reflux: Experimental studies of its etiology.J. Urol., 93, 165 (1965).
Stephens, F. D., Lenaghan, O.: The anatomical basis and dynamics of vesicoureteral reflux.J. Urol., 87, 669 (1962).
Torbey, K. Leadbetter, W. F.: Innervation of the bladder and lower ureter: Studies of pelvic nerve section and stimulation in the dog.J. Urol., 90, 395 (1963).
Elbadawi, A., Schenk, E.: A new theory of the innervation of bladder musculature. Part 2. The innervation apparatus of the ureterovesical junction.J. Urol., 105, 368 (1971).
Elbadawi, A.: Anatomy and function of the ureteral sheath.J. Urol., 102, 224 (1972).
Kaplan, N., Elkin, M., Sharkey, J.: Ureteral peristalsis and the autonomic nervous system.Invest. Urol., 5, 468 (1968).
Malin, J. M., Jr., Boyarsky, S.: The effect of cholinergic and adrenergic drug stimulation of detrusor muscle.Invest. Urol., 8, 286 (1970).
Elbadawi, A, Schenk, E. A.: A new theory of the innervation of bladder musculature. Part 3. Postganglionic synapses in uretero-vesico-urethral autonomic pathways.J. Urol., 105, 372 (1971).
Duarte-Escalante, L., Labay, P., Boyarsky, S.: The neurohistochemistry of mammalian ureter: A new combination of histochemical procedures to demonstrate adrenergic, cholinergic and chromaffin structures in ureter.J. Urol., 101, 803 (1969).
Hinman, F., Jr., Miller, E. R.: Mural tension in vesical disorders and ureteral reflux.J. Urol., 91, 33 (1964).
Corrierre, J. N., Jr., McClare, M. M. J. III., Lipschultz, L. I.: Contamination of bladder urine by urethral particles during voiding: Urethro-vesical reflux.J. Urol., 107, 399 (1972).
Politano, V. A., Leadbetter, W. F.: An operative technique for correction of vesicoureteral reflux.J. Urol., 79, 932 (1958).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Koyanagi, T., Ishikawa, T. & Tsuji, I. Vesico-ureteral reflux and uninhibited neurogenic bladder. International Urology and Nephrology 9, 217–224 (1977). https://doi.org/10.1007/BF02082166
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02082166