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Protective action of M- and N-cholinoceptor blockers in acute ammonium intoxication

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Atropine and d-tubocurarine are shown to prevent convulsions in rats and mice poisoned by ammonium acetate and to protect these animals from its toxic effects. Ammonium and lactate levels in their brain were found to correlate directly with ammonium toxicity.

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Authors and Affiliations

  1. Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Mosco

    E. A. Kosenko, Yu. G. Kaminskii, V. N. Korneev & L. D. Luk'yanova

  2. Laboratory of Biophysical Instrumentation, Institute of Cell Biophysics, Russian Academy of Sciences, Mosco

    E. A. Kosenko, Yu. G. Kaminskii, V. N. Korneev & L. D. Luk'yanova

  3. Laboratory of Bioenergetics, Institute of Pharmacology, Russian Academy of Medical Sciences, Mosco, Mosco

    E. A. Kosenko, Yu. G. Kaminskii, V. N. Korneev & L. D. Luk'yanova

Authors
  1. E. A. Kosenko
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  2. Yu. G. Kaminskii
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  3. V. N. Korneev
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  4. L. D. Luk'yanova
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, No 11, pp. 489–492, November, 1995

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Kosenko, E.A., Kaminskii, Y.G., Korneev, V.N. et al. Protective action of M- and N-cholinoceptor blockers in acute ammonium intoxication. Bull Exp Biol Med 120, 1111–1114 (1995). https://doi.org/10.1007/BF02445478

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  • DOI: https://doi.org/10.1007/BF02445478

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