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Potential activity of Ca2+/Mg2+-dependent endonuclease in endometrial hyperplasia and cancer

  • Oncology
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Abstract

Potential activity of Ca2+/Mg2+-dependent endonuclease in hyperplastic endometrial tissues is lower than in normal endometrium and practically absent in endometrial cancer tissue. Thus, molecular mechanisms of apoptosis regulation are disturbed even at the stage of hyperplasia.

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Authors and Affiliations

  1. Research Center of Obstetrics, Gynecology, Russian Academy of Medical Sciences, USSR

    M. M. Dement'eva, G. E. Chernukha, L. Z. Faizullin & G. T. Sukhikh

  2. Research Center of Perinatology, Russian Academy of Medical Sciences, USSR

    M. M. Dement'eva, G. E. Chernukha, L. Z. Faizullin & G. T. Sukhikh

  3. Institute of Biological Medicine, Moscow, USSR

    E. A. Kolobova, A. V. Zhdanov & D. A. Varlamov

  4. Moscow Municipal Oncology Dispensary, Moscow, USSR

    Yu. Yu. Tabakman & A. E. Ivanova

Authors
  1. E. A. Kolobova
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  2. A. V. Zhdanov
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  3. D. A. Varlamov
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  4. M. M. Dement'eva
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  5. G. E. Chernukha
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  6. L. Z. Faizullin
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  7. Yu. Yu. Tabakman
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  8. A. E. Ivanova
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  9. G. T. Sukhikh
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 6, pp. 683–687, June, 1999

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Kolobova, E.A., Zhdanov, A.V., Varlamov, D.A. et al. Potential activity of Ca2+/Mg2+-dependent endonuclease in endometrial hyperplasia and cancer. Bull Exp Biol Med 127, 624–627 (1999). https://doi.org/10.1007/BF02433297

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  • DOI: https://doi.org/10.1007/BF02433297

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