Abstract
Multiple biopsies were taken from 50 patients with endoscopic appearance of duodenitis in order to study the relationship between gastric metaplasia in duodenum and the presence ofCampylobacter-like organisms (CLOs) and the development of duodenal ulcer disease. Metaplasia was found in at least one biopsy specimen from 46 of the 50 patients; CLOs were seen in 25 of the 50 patients, only in metaplastic areas. In four cases a “transitional epithelium” with the presence of cells containing few apical mucoid granules and absorbent-type brush border as well as goblet cells was seen. In two cases, this epithelium was colonized by a small number of CLOs. Gastric heterotopia appears to be a rare condition.
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Caselli, M., Trevisani, L., Aleotti, A. et al. Gastric metaplasia in duodenal bulb andCampylobacter-like organisms in development of duodenal ulcer. Digest Dis Sci 34, 1374–1378 (1989). https://doi.org/10.1007/BF01538072
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DOI: https://doi.org/10.1007/BF01538072