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Comparison of scintigraphy with indium-111 leukocyte scan and ultrasonography in assessment of x-ray-demonstrated lesions of crohn's disease

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Abstract

The aim of this study was to compare the results obtained with an indium-111 scan with those obtained with less expensive and harmless ultrasonography to evaluate the location and inflammatory activity of Crohn's disease. Thirty-one patients previously studied with x-ray underwent abdominal111In scans and ultrasonography (US). Sensitivity and specificity of US in detecting lesions seen with111In scan were 77% and 92.8%, respectively. Sensitivity and specificity of111In scan in detecting x-ray-defined lesions were 69.2% and 92.7%; the figures for US were 73% and 93.3%, respectively. Considering the evaluation of disease activity, ultrasonographic bowel wall thickness was significantly related to scintigraphic intensity of emission (r=0.75 P<0.01). Our experience suggests that US provided information about the location and inflammatory activity of lesions similar to that obtained from111In scan.

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Authors and Affiliations

  1. Istituto di Clinica Medica e Gastroenterologia, Universitá di Bologna, Bologna, Italy

    Corrado Brignola MD, Clarissa Belloli MD, Primiano Iannone MD, Giuliana De Simone MD, Claudio Corbelli MD, Maurizio Levorato MD, Vincenzo Arienti MD, Luciana Boriani MD, Paolo Gionchetti MD, Andrea Belluzzi MD, Massimo Campieri MD, Giovanni Gasbarrini MD & Luigi Barbara MD

  2. Servizio di Medicina Nucleare, Ospedale S. Orsola-Malpighl, Bologna, Italy

    Corrado Brignola MD, Clarissa Belloli MD, Primiano Iannone MD, Giuliana De Simone MD, Claudio Corbelli MD, Maurizio Levorato MD, Vincenzo Arienti MD, Luciana Boriani MD, Paolo Gionchetti MD, Andrea Belluzzi MD, Massimo Campieri MD, Giovanni Gasbarrini MD & Luigi Barbara MD

  3. Istituto di Patologia Medica 1, Universitá di Bologna, Bologna, Italy

    Corrado Brignola MD, Clarissa Belloli MD, Primiano Iannone MD, Giuliana De Simone MD, Claudio Corbelli MD, Maurizio Levorato MD, Vincenzo Arienti MD, Luciana Boriani MD, Paolo Gionchetti MD, Andrea Belluzzi MD, Massimo Campieri MD, Giovanni Gasbarrini MD & Luigi Barbara MD

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  1. Corrado Brignola MD
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  2. Clarissa Belloli MD
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  3. Primiano Iannone MD
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  4. Giuliana De Simone MD
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  5. Claudio Corbelli MD
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  6. Maurizio Levorato MD
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  7. Vincenzo Arienti MD
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  8. Luciana Boriani MD
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  9. Paolo Gionchetti MD
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  10. Andrea Belluzzi MD
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  11. Massimo Campieri MD
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  12. Giovanni Gasbarrini MD
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  13. Luigi Barbara MD
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Brignola, C., Belloli, C., Iannone, P. et al. Comparison of scintigraphy with indium-111 leukocyte scan and ultrasonography in assessment of x-ray-demonstrated lesions of crohn's disease. Digest Dis Sci 38, 433–437 (1993). https://doi.org/10.1007/BF01316495

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  • DOI: https://doi.org/10.1007/BF01316495

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