Summary
The influence of lithium on aggressive behavior was studied in Siamese fighting fish, mice and golden hamsters. The fish stopped fighting when exposed to concentrations of 10 to 30 meq/l LiCl in the surrounding water. Also in mice and hamsters which ingested LiCl with the drinking fluid lithium abolished intraspecific aggression. Measurements of plasma and brain lithium levels revealed astonishing individual differences in the concentrations which were necessary for the antiaggressive effect. In all species normal aggressive behavior reappeared after lithium treatment was discontinued.
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Weischer, M.L. Über die antiaggressive Wirkung von Lithium. Psychopharmacologia 15, 245–254 (1969). https://doi.org/10.1007/BF00401678
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DOI: https://doi.org/10.1007/BF00401678