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Blood and urine levels of N,N-dimethyltryptamine following administration of psychoactive dosages to human subjects

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Abstract

Psychoactive doses (0.7 mg/kg) of the hallucinogen N,N-dimethyltryptamine (DMT) were administered intramuscularly to 11 normal subjects. A gas chromatographic-mass spectrometric isotope dilution determination of DMT concentrations in whole blood and urine revealed that only a fraction of the injected dose was recovered and the blood DMT concentrations had a very similar time course o the subjectively reported “high”.

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Kaplan, J., Mandel, L.R., Stillman, R. et al. Blood and urine levels of N,N-dimethyltryptamine following administration of psychoactive dosages to human subjects. Psychopharmacologia 38, 239–245 (1974). https://doi.org/10.1007/BF00421376

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