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Einfache Methode zur Erzeugung einer sicheren, irreversiblen Hirnischämie beim Hund ohne Eingriff in die übrige Kreislauffunktion

Simple method for induction of complete, irreversible cerebral ischemia in the dog without disturbance of the general circulation

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Summary

A simple technique is described, which permits the interruption of circulation of blood to the intracranial nervous system of the dog without production of general circulatory collapse. The injection of a special polymerising mixture into both common carotide arteries results in a complete arrest of the cerebral circulation within a few seconds. The immediate and complete arrest of the cerebral circulation is proved electroencephalographically and by macerated preparations of the injected brains.

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Authors and Affiliations

  1. Lehrstuhl und Abteilung für Experimentelle Chirurgie der Chirurgischen Universitäts-Klinik Köln-Lindenthal, Josef Stelzmann-Str. 9, D-5000, Köln-Lindenthal, Bundesrepublik Deutschland

    J. H. Fischer, F. W. Schildberg & W. Isselhard

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  1. J. H. Fischer
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  2. F. W. Schildberg
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  3. W. Isselhard
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Fischer, J.H., Schildberg, F.W. & Isselhard, W. Einfache Methode zur Erzeugung einer sicheren, irreversiblen Hirnischämie beim Hund ohne Eingriff in die übrige Kreislauffunktion. Pflugers Arch. 335, 335–339 (1972). https://doi.org/10.1007/BF00586223

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  • DOI: https://doi.org/10.1007/BF00586223

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