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Skinned smooth muscle: calcium-calmodulin activation independent of myosin phosphorylation

  • Excitable Tissues and Central Nervous Physiology
  • Short Communication
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Abstract

In chemically skinned chicken gizzard smooth muscle fibers investigated shortly after preparation, a contraction may be induced by calcium and calmodulin which is independent of myosin phosphorylation at intermediate Ca2+-concentrations. However, fibers stored for a prolonged period also contract in the absence of exogenous calmodulin and exhibit a close relationship between force development and myosin phosphorylation.

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Authors and Affiliations

  1. II. Physiologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 326, D-6900, Heidelberg, Germany

    J. Wagner & J. C. Rüegg

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  1. J. Wagner
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  2. J. C. Rüegg
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Wagner, J., Rüegg, J.C. Skinned smooth muscle: calcium-calmodulin activation independent of myosin phosphorylation. Pflugers Arch. 407, 569–571 (1986). https://doi.org/10.1007/BF00657520

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  • DOI: https://doi.org/10.1007/BF00657520

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