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Correlation between cerebral blood volume and cerebral blood flow in the cat

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Summary

Blood flow and blood volume were measured simultaneously in the same cerebral region in anaesthetized cats with controlled respiration. The measurements were made with the same scintillation-detector, using the freely diffusible indicator 133 Xenon for flow determinations and the intra-vascular indicator RISA (131I) for volume recordings. A very high correlation was found between volume and flow changes (r = .96, p < 0.001). This finding indicates that variations of regional cerebral blood volume are accompanied by proportional blood flow changes.

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Attaché de recherche au C.N.R.S., Laboratoire de Neurophysiologie, Hopital Henri Rouselle, Paris, France.

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Risberg, J., Ancri, D. & Ingvar, D.H. Correlation between cerebral blood volume and cerebral blood flow in the cat. Exp Brain Res 8, 321–326 (1969). https://doi.org/10.1007/BF00234379

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