Summary
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1.
Properties of synaptic transmission during and after repetitive activation of the newly formed cortico-rubral synapses were examined in the red nucleus neurons (RN) of cats after lesions of the nucleus interpositus of the cerebellum (chronic cats) as well as in normal ones.
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2.
A prominent facilitation of the amplitude of cortico-rubral unitary EPSPs was observed in both normal and chronic cats when a stimulus to the cerebral peduncle (CP) was preceded by another stimulus by 2–50 msec.
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3.
Time course of the facilitation shows that it attains maximum at the interval of about 3 msec and decays approximately exponentially lasting for 50 msec or more.
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4.
When three successive stimuli of identical intensity were applied to CP, the degree of facilitation was more prominent than that for double shock.
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5.
There was a positive correlation between the time to peak of the cortico-rubral EPSPs and their maximum value of facilitation.
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6.
The posttetanic potentiation of the cortico-rubral EPSPs was observed after tetanic stimulation to CP in chronic and normal cats. It lasts for a few minutes in both cases.
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Murakami, F., Tsukahara, N. & Fujito, Y. Properties of the synaptic transmission of the newly formed cortico-rubral synapses after lesion of the nucleus interpositus of the cerebellum. Exp Brain Res 30, 245–258 (1977). https://doi.org/10.1007/BF00237254
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DOI: https://doi.org/10.1007/BF00237254