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Radiation necrosis of the brain. Neuroradiological considerations with computed tomography

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Summary

In cases with radiation necrosis of the brain, conventional neuroradiological examinations usually demonstrate only an avascular mass lesion impossible to differentiate from intracerebral tumor or hemorrhage. Computed tomography, performed in addition to angiography in three cases, consistantly demonstrated the radiation necrosis as a low density area exhibiting enhancement following infusion of contrast medium. The importance of recognizing radiation necrosis as a differential diagnosis to brain neoplasm is emphasized.

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References

  1. Foltz, E.L., Holyoke, J. B., Heyl, H.L.: Brain necrosis following X-ray therapy. J. Neurosurg. 10, 423–429 (1953)

    Google Scholar 

  2. Lowenberg-Scharenberg, K., Basset, R. C.: Amyloid degeneration of the human brain follwing X-ray therapy. J. Neuropathol. Exp. Neurol. 9, 93–102 (1950)

    Google Scholar 

  3. Eyster, E. F., Nielsen, S. L., Sheline, G. E.: Cerebral radiation necrosis simulating a brain tumor. J. Neurosurg. 39, 267–271 (1974)

    Google Scholar 

  4. Lampert, P. W., Davis, R. L.: Delayed effects of radiation on the human central nervous systems: “early” and “late” delayed reactions. Neurology 14, 912–917 (1964)

    Google Scholar 

  5. Almquist, S., Dahlgren, S., Notter, G., Sundbom, L.: Brain necrosis after irradiation of the hypophysis in Cushing's disease: report of a case. Acta radiol. (Ther.) 2, 179–188 (1964)

    Google Scholar 

  6. Crompton, M. R., Layton, D. D.: Delayed radionecrosis of the brain following therapeutic X-radiation of the pituitary. Brain 84, 85–101 (1961)

    Google Scholar 

  7. Pech, F. C., Jr., McGovern, E. R.: Radiation necrosis of the brain in acromegaly. J. Neurosurg. 25, 536–542 (1966)

    Google Scholar 

  8. Richmond, J. J.: Discussion on pituitary tumours: the role of radiotherapy. Proc. Roy. Soc. Med. 51, 911–914 (1958)

    Google Scholar 

  9. Lindgren, M.: On tolerance of brain tissue and sensitivity of brain tumours to irradiation. Acta radiol. (Suppl.) 170, 1–73 (1958)

    Google Scholar 

  10. Ghatak, N. R., White, B. E.: Delayed radiation necrosis of the hypothalamus: report of a case simulating recurrent craniopharyngioma. Arch. Neurol. 21, 425–430 (1969)

    Google Scholar 

  11. Rubinstein, L. J.: Tumors of the central nervous system (In) Atlas of tumor pathology, 2nd series, Fasc 6, p. 351. Washington, D. C.: Armed Forces Institute of Pathology 1972

    Google Scholar 

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Brismar, J., Roberson, G.H. & Davis, K.R. Radiation necrosis of the brain. Neuroradiological considerations with computed tomography. Neuroradiology 12, 109–113 (1976). https://doi.org/10.1007/BF00333126

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  • DOI: https://doi.org/10.1007/BF00333126

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