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The efficiency of protective gloves used in the handling of cytotoxic drugs

  • Original Articles
  • Handing of Cytotoxic Drugs, Protective Gloves
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Cancer Chemotherapy and Pharmacology Aims and scope Submit manuscript

Summary

A range of clinical and industrial gloves have been evaluated to determine their ability to exclude penetration by cytotoxic drugs.

Radiolabelled cyclophosphamide, methotrexate, daunomycin, cytosine arabinoside, and vincristine sulphate were studied in an equilibrium dialysis system in which the glove material was used as the dialysis membrane.

The thicker gloves were the most effective, but very little drug crossed any of the gloves tested under laboratory conditions. Further studies to evaluate gloves in conditions of clinical use are now needed.

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Authors and Affiliations

  1. ICRF Department of Medical Oncology, St Bartholomew's Hospital, EC1A 7BE, London, England

    M. L. Slevin

  2. Hackney Hospital, EC1A 7BE, London, England

    M. L. Slevin

  3. Department of Clinical Pharmacology, St Bartholomew's Hospital, EC1A 7BE, London, England

    L. M. Ang, A. Johnston & P. Turner

Authors
  1. M. L. Slevin
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  2. L. M. Ang
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  3. A. Johnston
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  4. P. Turner
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Slevin, M.L., Ang, L.M., Johnston, A. et al. The efficiency of protective gloves used in the handling of cytotoxic drugs. Cancer Chemother. Pharmacol. 12, 151–153 (1984). https://doi.org/10.1007/BF00256536

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  • DOI: https://doi.org/10.1007/BF00256536

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