Summary
A massive congenital benign teratoma grossly replacing the cerebral hemispheres has been examined by light and electron microscopy. The tumor contained tissues derived from all three germ layers. The cerebellum showed morphological features suggesting a state of maturation equivalent to that of 20 to 25 weeks of gestation. The tumor is discussed in the light of present theories on the pathogenesis of teratomas.
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This work was supported by International Post-Doctoral Fellowship No. 1 FO5 TWO 02078-01, by Graduate Neuropathology Training Grant No. 5-TO1-NS-5500-09 from the National Institute of Neurological Diseases and Stroke, National Institutes of Health, U.S.P.H.S. and by The Cancer Research Foundation and Council of Medical Research, Denmark.
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Vraa-Jensen, J. Massive congenital intracranial teratoma. Acta Neuropathol 30, 271–276 (1974). https://doi.org/10.1007/BF00688927
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DOI: https://doi.org/10.1007/BF00688927