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Primary cerebral neuroblastoma: A light and electron microscopic study

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Summary

A small-cell neoplasm in the left temporal lobe of a 10 and a half year old boy was studied by light and electron microscopy. Routine sections of the mass showed a differentiating neuroblastoma with Homer Wright rosettes, several foci of immature neoplastic neurons (ganglion cells), many mitoses, arcas of necrosis and tumor vessels showing endothelial proliferation. Ultrastructurally, most cells resembled early fetal neuroblasts and also were similar to those in murine and peripheral human neuroblastomas.

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Authors and Affiliations

  1. Cajal Laboratory of Neuropathology, Los Angeles County-University of Southern California Medical Center, 90033, Los Angeles, California, USA

    Roy H. Rhodes, Richard L. Davis, Steven H. Kassel & Brian H. Clague

  2. Department of Pathology, University of Southern California School of Medicine, 90033, Los Angeles, California, USA

    Roy H. Rhodes, Richard L. Davis, Steven H. Kassel & Brian H. Clague

  3. Valley Children's Hospital, 93702, Fresno, California, USA

    Roy H. Rhodes, Richard L. Davis, Steven H. Kassel & Brian H. Clague

Authors
  1. Roy H. Rhodes
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  2. Richard L. Davis
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  3. Steven H. Kassel
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  4. Brian H. Clague
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Supported in part by Biomedical Rescarch Support Grant 5 S07 RR05356-13 from the Department of Health, Education and Welfre, Division of Research Sources

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Rhodes, R.H., Davis, R.L., Kassel, S.H. et al. Primary cerebral neuroblastoma: A light and electron microscopic study. Acta Neuropathol 41, 119–124 (1978). https://doi.org/10.1007/BF00689762

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  • DOI: https://doi.org/10.1007/BF00689762

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