Summary
Three surgically removed primary arachnoidal cysts were studied with scanning electron microscopy (SEM) and two of the cases with transmission electron microscopy (TEM). The cells lining the cyst cavity had microvilli at the surface, true cilia were absent. In the cytoplasm multivesicular bodies, many pinocytotic vesicles, some large vacuoles and strands of tonofilaments were prominent features. The cells were interconnected by desmosome-like junctions and were interconnected by desmosome-like junctions and were separated from the surrounding tissue by a distinct but sometimes incomplete basal membrane.
Based on these findings it is concluded that arachnoid cysts are derived from the outer arachnoid cells (subdural neurothelium), the formation of the cysts being attributable to secretory capacity of the subdural neurothelium.
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Allen, D. J., Didio, L. J. A.: Scanning and transmission electron microscopy of the encephalic meninges in dogs. J. Submic. Cytol.9, 1–22 (1977)
Anderson, F. M., Landing, B. H.: Cerebral arachnoid cysts in infants. J. Pediatr.69, 88–96 (1966)
Anderson, D. R.: Ultrastructure of meningeal sheaths. Arch. Ophthalmol.82, 659–674 (1969)
Drochmans, P., Wanson, J. C., Mosselmans, R.: Isolation and subfractionation on Ficoll gradient of adult rat hepatocytes. Size, morphology and biochemical characteristics of cell fractions. J. Cell. Biol.66, 1–22 (1975)
Fawcett, D. W.: Physiologically significant specializations of the cell surface. Circulation26, 1105–1132 (1962)
Ghatak, N. R., Mushrush, G. J.: Supratentorial intra-arachnoid cyst. J. Neurosurg.35, 477–482 (1971)
Harrison, M. J. G.: Cerebral arachnoid cysts in children. J. Neurol. Neurosurg. Psychiatry34, 316–323 (1971)
Holst, S.: Congenital intracranial arachnoid cysts. J. Oslo City Hosp.15, 113–120 (1965)
Jakubiak, P., Dunsmore, R. H., Beckett, R. S.: Supratentorial brain cysts. J. Neurosurg28, 129–136 (1968)
Lie, T. A.: Congenital arachnoidal cysts in the temporal fossa. In: Progress in Paediatric Neurosurgery (eds. K. A. Bushe, O. Spoerri, J. Shaw), pp. 219–220. Stuttgart: Hippocrates 1974
Lopes, C. A. S., Mair, W. G. P.: Ultrastructure of the arachnoid membrane in man. Acta Neuropathol. (Berl.)28, 167–173 (1974)
Milhorat, T. H.: Structure and function of the choroid plexus and other sites of cerebrospinal fluid formation. Internat. Rev. Cytol.47, 225–288 (1976)
Oschman, J. L.: Mechanism and control of fluid secretion. Yale J. Biol. Med.50, 133–152 (1977)
Patrick, B. S.: Ependymal cyst of the Sylvian fissure. J. Neurosurg.35, 751–754 (1971)
Peters, A., Palay, S. L., Webster, F. de: The fine structure of the nervous system. The neurons and supporting cells. Philadelphia: W. B. Saunders 1976
Rascol, M. M., Izard, J. Y.: The subdural neurothelium of the cranial meninges in man. Anat. Rec.186, 429–436 (1976)
Robinson, R. G.: Intracranial collections of fluid with local bulging of the skull. J. Neurosurg.12, 345–353 (1955)
Starkman, S. P., Brown, T. C., Linell, E. A.: Cerebral arachnoid cysts. J. Neuropathol. Exp. Neurol.17, 484–500 (1958)
Triphathy, R. C.: Ultrastructure of the arachnoid mater in relation to outflow of cerebrospinal fluid. Lancet1, 8–11 (1973)
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Go, K.G., Houthoff, H.J., Blaauw, E.H. et al. Morphology and origin of arachnoid cysts scanning and transmission electron microscopy of three cases. Acta Neuropathol 44, 57–62 (1978). https://doi.org/10.1007/BF00691640
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DOI: https://doi.org/10.1007/BF00691640