Skip to main content
Log in

Topographic distribution pattern of Lafora-like bodies in the spinal cord of some animals

  • Short Original Communications
  • Published:
Acta Neuropathologica Aims and scope Submit manuscript

Summary

The topographic distribution pattern and morphological features of Lafora-like bodies in the spinal cord of the dog, cat, fox, and baboon were examined by light and electron microscopy. The caudal lumbar and the coccygeal parts of the spinal cords were the predilection sites for the bodies in all animals and were very prominent in the ventral columns and intermediate substance. The bodies mainly composed of branching filaments were preferentially located in neuronal processes and rarely in astrocytes. The histochemical characteristics of the bodies were identical in all animals and consisted mainly of polyglucosan.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Averback, P., Langevin, H.: Corpora amylacea of the spinal cord and peripheral nervous system. Arch. Neurol.35, 95–96 (1978)

    Google Scholar 

  • Hoerlein, B. F.: Canine neurology, pp. 39–47. Philadelphia, London, Toronto: Saunders 1971

    Google Scholar 

  • Sakai, M., Austin, J., Witmer, F., Trueb, L.: Studies of corpora amylacea. I. Isolation and preliminary characterization by chemical and histochemical techniques. Arch. Neurol.21, 526–544 (1969)

    Google Scholar 

  • Sakai, M., Austin, J., Witmer, F., Trueb, L.: Studies in myoclonus epilepsy (Lafora body form). II. Polyglucosans in the systemic deposits myoclonus epilepsy and in corpora amylacea. Neurology (Minneap.)20, 160–176 (1970)

    Google Scholar 

  • Suzuki, Y., Akiyama, K., Suu, S.: Lafora-like inclusion bodies in the CNS of the aged dogs. Acta Neuropathol. (Berl.)44, 217–222 (1978)

    Google Scholar 

  • Suzuki, Y., Kamiya, S., Ohta, K., Suu, S.: Lafora-like bodies in a cat. Case report suggestive of glycogen metabolism disturbances. Acta Neuropathol. (Berl.)48, 55–58 (1979a)

    Google Scholar 

  • Suzuki, Y., Ohta, K., Auu, S.: Correlative studies of axonal spheroids and Lafora-like bodies in aged dogs. Acta Neuropathol.48, 77–81 (1979b)

    Google Scholar 

  • Takahashi, K., Agari, M., Nakamura, H.: Intra-axonal corpora amylacea in ventral and lateral horns of the spinal cord. Acta Neuropathol. (Berl.)31, 151–158 (1975)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Suzuki, Y., Ohta, K., Kamiya, S. et al. Topographic distribution pattern of Lafora-like bodies in the spinal cord of some animals. Acta Neuropathol 49, 159–161 (1980). https://doi.org/10.1007/BF00690756

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00690756

Key words

Navigation