Summary
Intracytoplasmic cosinophilic inclusions were found by light microscopy in the thalamic neurons of 35 consecutive normal adult brains and in a case of myotonic dystrophy, but not in six newborn children, including one with myotonic dystrophy. Histochemical tests suggested a protein composition. Ultrastructurally, the inclusions were composed of stacks of parallel alternating dark and light rectilinear profiles not surrounded by a limiting membrane. Such inclusions are a virtually constant finding in the adult human thalamus and probably represent sites of neuronal protein storage.
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Peña, C.E. Intracytoplasmic neuronal inclusions in the human thalamus. Acta Neuropathol 52, 157–159 (1980). https://doi.org/10.1007/BF00688015
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DOI: https://doi.org/10.1007/BF00688015