Summary
The ultrastructure of a typical case of Abrikossoff's tumor of the tongue is described. The histogenesis of the granular cells as well as the nature of the virus-like particles are discussed in relation to published ultrastructural observations.
The AA maintain the neurogenic origin of granular cells, however, a possible multicentric origin cannot be ruled out.
Zusammenfassung
Die Ultrastruktur eines typischen Abrikossoff-Tumors der Zunge wird beschrieben. Die Histogenese der Granularzellen wie auch die Morphologie der virusartigen Partikel werden im Hinblick auf die bisher vorliegenden ultrastrukturellen Ergebnisse diskutiert. Die Abrikossoff-Tumorzellen behalten die neurogene Morphologie der Granularzellen, eine multizentrische Herkunft kann jedoch nicht ausgeschlossen werden.
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References
Abrikossoff, A.: Über Myome, ausgehend von der quergestreiften willkürlichen Muskulatur. Virchows Arch. path. Anat.206, 215–233 (1926).
—: Weitere Untersuchungen über Myoblastenmyome. Virchows Arch. path. Anat.280, 723–740 (1931).
Azzopardi, I. G.: Histogenesis of the granular cell myoblastoma. J. Path. Bact.71, 85–94 (1956).
Bangle, R.: A morphological and histochemical study of the granular cell myoblastoma. Cancer Res.5, 950–965 (1952).
Caputo, R., Lombardi, L.: Quadri ultrastrutturali dell'epidermide umana normale. Atti Accad. med. lombarda18, 72–77 (1963).
Fisher, E. R., Wechsler, H.: Granular cell myoblastoma—a misnomer. Electron microscopic and histochemical evidence concerning its Schwann cell derivation and nature (granular cell Schwannoma). Cancer Res.15, 936–954 (1962).
Gray, S. H., Gruenfeld, G. E.: Myoblastoma. Amer. J. Cancer30, 699–708 (1937).
Haisken, W., Langer, E.: Die submikroskopische Struktur des sogenannten Myoblastenmyoms. Frankfurt. Z. Path.71, 600–612 (1962).
Klemperer, P.: Myoblastoma of striated muscle. Amer. J. Cancer20, 324–337 (1934).
Millonig, G.: Further observations on a phosphate buffer for osmium solutions in fixation. In: Proceedings of the Fifth Congress on Electron Microscopy, vol. 2, p. 8. Philadelphia Ed. S. S. Breese, Jr. New York: Academic Press 1962.
Misugi, K., Misugi, N., Newton, W.: Ultrastructure of so-called granular cell myoblastoma. Yokohama med. Bull.18, 225–234 (1967).
Moscovic, E., Azar, H.: Multiple granular cell tumors (Myoblastomas). Cancer Res.20, 2032–2047 (1967).
Pearse, A. G.: The histogenesis of granular cell myoblastoma—granular cell perineural fibroblastoma. J. Path. Bact.62, 351–362 (1950).
Shear, M.: The histogenesis of the so called granular cell myoblastoma. J. Path. Bact.80, 225–228 (1960).
Sobel, H. J., Crurg, J.: Granular cells and granular cell lesions. Arch. Path.77, 132–141 (1964).
Takebayashi, S.: Granular cell myoblastoma. Gan no Rinsho10, 550–553 (1964).
Wegelin, C.: Die Natur der sog. Myoblastentumoren. Schweiz. Z. Path.10, 631–653 (1947).
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Caputo, R., Bellone, A.G. & Tagllavini, R. Ultrastructure of the granular cell myoblastoma. Arch. Derm. Forsch. 242, 127–136 (1972). https://doi.org/10.1007/BF00595561
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DOI: https://doi.org/10.1007/BF00595561