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Observations of the succinic dehydrogenase activity in the hair cells of shaker-1 mouse

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Summary

The SDH activity of the hair cells of sh-1 mice was topographically examined during several days after birth, using the surface preparation method. The activity of this enzyme in sh-1 mice decreased as the animals got older, the outer hair cells being most affected. The level of enzyme activity was different in the three different turns of Corti's organ, especially for the outer hair cells. There was no difference in the activity among the three rows of the outer hair cells.

Zusammenfassung

Bei 60 sh-1 Mäusen (120 Cochleae) unterschiedlichen Alters (15 bis 100 Tage) wurde histochemisch die SDH-Aktivität im Corti'schen Organ untersucht. Es fand sich, daß mit zunehmendem Alter der Tiere die Enzymaktivität abnahm, wobei die äußeren Haarzellen am stärksten betroffen wurden. Die Befunde waren in den verschiedenen Schneckenwindungen unterschiedlich. Innerhalb der drei Reihen der äußeren Haarzellen dagegen gab es keinen Unterschied in der Aktivität.

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  1. Hals-Nasen-Ohren-Univ.-Klinik Frankfurt a. M., Bundesrepublik Deutschland

    T. Yamashita & J. T. -Y. Chou

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  1. T. Yamashita
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  2. J. T. -Y. Chou
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Yamashita, T., Chou, J.T.Y. Observations of the succinic dehydrogenase activity in the hair cells of shaker-1 mouse. Arch Otorhinolaryngol 208, 97–105 (1974). https://doi.org/10.1007/BF00453923

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  • DOI: https://doi.org/10.1007/BF00453923

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