Summary
PGM1 subtypes were determined in red cell hemolysates by isoelectric focusing on agarose gel plates. By this modified procedure PGM1 subtypes may be readily classified. Nine of the 10 expected phenotypes were found in a sample of 470 unrelated individuals from Southern Germany. The frequencies for the four alleles were found to be: PGM 1+1 = 0.6212, PGM 1-1 = 0.1224, PGM 2+1 = 0.2043, PGM 2-1 = 0.0521.
Zusammenfassung
Der PGM1-Polymorphismus wurde mit Hilfe der Isoelektrofokussierung auf Agarose-Gel-Platten untersucht. Mit dieser modifizierten Methode lassen sich die PGMI-Untergruppen an Hämolysaten ohne Schwierigkeiten klassifizieren. Neun der erwarteten zehn Phänotypen wurden in einer Stichprobe von. 470 nichtverwandten Personen aus Süddeutschland beobachtet. Folgende Allelhäufigkeiten wurden ermittelt: PGM 1+1 = 0,6212, PGM 1-1 = 0,1224, PGM 2+1 = 0,2043, PGM 2-1 = 0,0521.
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Weidinger, S., Schwarzfischer, F. PGM1 subtypes determined by agarose gel isoelectrofocusing. Z Rechtsmed 84, 221–224 (1980). https://doi.org/10.1007/BF01866573
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DOI: https://doi.org/10.1007/BF01866573