Skip to main content
Log in

Intracisternal virus-like particles in a human pituitary adenoma

  • Published:
Zeitschrift für Krebsforschung und Klinische Onkologie Aims and scope Submit manuscript

Summary

Electron microscopy revealed the presence of intracisternal virus-like particles in a mixed pituitary adenoma consisting of growth hormone cells and prolactin cells. The tumor was removed by surgery from a 48 year old man with a multiple endocrine adenomatosis type I syndrome. The significance of virus-like particles in the pathogenesis of pituitary adenomas remains to be elucidated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Bernhard,W.: The detection and study of tumor viruses with the electron microscope. Cancer Res. 20, 712–727 (1960)

    Google Scholar 

  • Dalton,A.J.: Observations on the details of ultrastructure of a series of type C viruses. Cancer Res. 32, 1351–1353 (1972a)

    Google Scholar 

  • Dalton,A.J.: RNA tumor viruses. Terminology and ultrastructural aspects of virion morphology and replication. J. nat. Cancer Inst. 49, 323–327 (1972b)

    Google Scholar 

  • Feldman,D.: An electron microscopic study of virus particles in Rhesus monkey placenta (C-type particles/chorionic villi/decidua basalis). Proc. nat. Acad. Sci. (Wash.) 72, 118–121 (1975)

    Google Scholar 

  • Feldman,D.G., Ehrenreich,T., Gross,L.: Brief communication: Type-C virus particles in a feline angioma: a case report. J. nat. Cancer Inst. 53, 1843–1846 (1974)

    Google Scholar 

  • Horvath,E., Kovacs,K.: Misplaced exocytosis. Distinct ultrastructural feature in some pituitary adenomas. Arch. Path. 97, 221–224 (1974)

    Google Scholar 

  • Kovacs,K., Horvath,E., Corenblum,B., Sirek,A.M.T., Penz,G., Ezrin,C.: Pituitary chromophobe adenomas consisting of prolactin cells. A histologic, immunocytological and electron microscopic study. Virchows Arch. A path. Anat. 366, 113–123 (1975)

    Google Scholar 

  • Petrea,I., Gardner,W.U.: Fine structure of pituitary tumors and transplants in mice: effects on the prostate. Int. J. Cancer 11, 40–57 (1973a)

    Google Scholar 

  • Petrea,I., Gardner,W.U.: Virus morphogenesis in a mouse lymphoma. Cancer Res. 33, 2291–2299 (1973b)

    Google Scholar 

  • Rimoin,D.L., Schimke,R.N.: Genetic disorders of the endocrine glands, pp. 200–205 St. Louis: C.V.MosbyCo. 1971

    Google Scholar 

  • Suggestions for the classification of oncogenic RNA viruses. J. nat. Cancer Inst. 37, 395–397 (1966)

    Google Scholar 

  • Yagi,M.J., Hamamoto,S.T., Duafala,J.D., Pitelka,D.R.: Brief communication: Atypical C particles in adenocarcinomas induced by implantation of Fuku cells. J. nat. Cancer Inst. 53, 1835–1837 (1974)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kovacs, K., Horvath, E. & Kerenyi, N.A. Intracisternal virus-like particles in a human pituitary adenoma. Z. Krebsforsch. 85, 111–115 (1976). https://doi.org/10.1007/BF00304943

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00304943

Keywords

Navigation