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PAL-test for malignant disease

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Summary

Peripheral blood lymphocytes from a total of 300 subjects including normal controls and patients with malignant and non-malignant disorders were investigated to determine their ability to agglutinate with Poly-l-lysine 3400 (PAL-test). A high level of association between clinically evident cancer and a positive reaction was confirmed.

Lymphocytes from 72 of 90 patients with malignant diseases as well as 33 of 140 patients with non-malignant processes showed positive reactions. All healthy controls were negative. The positive evidence of the PAL-test amounted to over 80%. The results and possible mechanisms of the PAL-test are discussed.

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Bauer, H.W., Ax, W. PAL-test for malignant disease. Z. Krebsforsch. 92, 35–40 (1978). https://doi.org/10.1007/BF00284092

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  • DOI: https://doi.org/10.1007/BF00284092

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