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D21S210: A highly polymorphic (GT)n marker closely linked to the β-amyloid protein precursor (APP) gene

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Abstract

We describe a highly polymorphic (GT)n repeat with 14 alleles that is closely linked to the amyloid precursor protein (APP) gene on human chromosome 21. This marker, D21S210, will be useful for studies of linkage of disorders such as Alzheimer disease to the APP gene.

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Authors and Affiliations

  1. Center for Medical Genetics, Johns Hopkins University School of Medicine, 600 North Wolfe Street, 21205, Baltimore, MD, USA

    Andrew C. Warren, Melvin G. McInnis, Marianna Kalaitsidaki & Stylianos E. Antonarakis

  2. Department of Psychiatry, Johns Hopkins University School of Medicine, 600 North Wolfe Street, 21205, Baltimore, MD, USA

    Andrew C. Warren & Melvin G. McInnis

  3. Department of Human Genetics, University of Pittsburgh, 15261, Pittsburgh, PA, USA

    Tara K. Cox, Jillian Blaschak & Aravinda Chakravarti

  4. Department of Psychiatry, University of Pittsburgh, 15261, Pittsburgh, PA, USA

    Aravinda Chakravarti

Authors
  1. Andrew C. Warren
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  2. Melvin G. McInnis
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  3. Marianna Kalaitsidaki
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  4. Tara K. Cox
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  5. Jillian Blaschak
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  6. Aravinda Chakravarti
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  7. Stylianos E. Antonarakis
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Warren, A.C., McInnis, M.G., Kalaitsidaki, M. et al. D21S210: A highly polymorphic (GT)n marker closely linked to the β-amyloid protein precursor (APP) gene. Hum Genet 91, 87–88 (1993). https://doi.org/10.1007/BF00230232

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  • DOI: https://doi.org/10.1007/BF00230232

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