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Studies on the juxtaglomerular apparatus

V. The juxtaglomerular apparatus in Tupaia with special reference to intercellular contacts

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Summary

The vascular pole of the juxtaglomerular apparatus in Tupaia belangeri was studied with special reference to the intercellular contacts of the periendothelial cells and the endothelium of the vas afferens. The periendothelial cells of the vascular pole of the glomerulum are connected by numerous gap junctions; and the granulated epithelial cells are suggested to form a functional unit. Probably there is a continuity of this system troughout the entire vascular pole including (1) all granulated cells, (2) all lacis cells, (3) the mesangium cells and (4) the adjacent smooth muscle cells of the vas afferens and vas efferens. Analysis of the endothelial junctions shows a zonular arrangement of tight junctions indicating a rather tight blood-tissue barrier next to the glomerular vascular pole. The ultrastructure of the different cell types of the vas afferens is also described, emphasizing the granulated epithelial cells and their innervation.

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Authors and Affiliations

  1. Departments of Anatomy and Physiology, University of Heidelberg, Germany

    W. G. Forssmann & R. Taugner

Authors
  1. W. G. Forssmann
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  2. R. Taugner
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Additional information

Supported by the “German Research Foundation”, SFB 90 Carvas Heidelberg, Germany.

We thank cand. med. P. Zahn and Mrs. B. Brühl for technical help and Mrs. R. Botz, M. Wybraniec and J. Greenberg in preparing the manuscript

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Forssmann, W.G., Taugner, R. Studies on the juxtaglomerular apparatus. Cell Tissue Res. 177, 291–305 (1977). https://doi.org/10.1007/BF00220305

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