Abstract
An apparatus and an electrode for early receptor potential recordings in clinical routine are introduced. One-hundred and eighty normal eyes were compared with cases of diffuse and localized retinal diseases. In retinitis pigmentosa patients a decrease in R1 and R2 amplitudes and in some cases a much faster time course was found. Eyes with circumscribed retinal affectations produced a wide variety of amplitudes, overlapping with the range of normals. In cases of monochromatism, the ERP recording established the diagnosis because of an absent R1 wave.
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Arden, GB, Ikeda, H and Siegel, IM (1966) Effects of light adaptation on the early receptor potential. Vision Res 6: 357–371
Brown, KT and Crawford, JM (1967) Melanin and the rapid light-evoked responses from the pigment epithelium cells of the frog eye. Vision Res 7: 165–178
Carr, RE and Siegel, IM (1970) Action spectrum of the human early receptor potential. Nature 204: 88–89
Dodt, E (1976) Möglichkeiten der ophthalmologischen Diagnostik. Med Klin 71: 2141–2151
Galloway, NR (1967) Early receptor potential in the human eye. Br J Ophthalmol 51: 261–264
Galloway, NR (1968) The clinical value of the human early receptor potential. In: Advances in Electrophysiology and Pathology of the Visual System (6th ISCERG Symposium), ed: Schmöger, E. Leipzig, Edition Leipzig, pp 403–407
Goldstein, EB and Berson, EL (1969) Rod and cone contributions to the human early receptor potential. Vision Res 10: 207–218
Kawasaki, K (1966) The early receptor potential in the human electroretinogram. Acta Soc Ophthalmol Jpn 70: 1594–1601
Kurachi, Y, Yonemura, D and Kawasaki, K (1967) Application of automatic clamp of starting point of sweep to clinical electroretinography. Jpn J Clin Ophthalmol 21: 649–651
Lapp, ER and Tanabe, J (1981) Das Frühe Rezeptorenpotential (ERP): Aktionsspektren bei normal Fartüchtigen und Farbblinden. Ber Dtsch Ophthalmol Ges 78: 727–731
Marinho, A and Sampaio Melo, J (1983) O estudo do ERP. Rev Soc Port Oftal 9: 15–20
Müller, W, Töpke, H, Gauss, J and Pietscher, S (1982) The inter- and intraindividual variations of the early receptor potentials (ERP). Graefes Arch Klin Exp Ophthalmol 218: 222–224
Sieving, PA and Fishman, GA (1982) Rod contribution to the human early receptor potential (ERP) estimated from monochromat's data. Doc Ophthalmol Proc Ser 31: 95–102
Tamai, A and Holland, MG (1974) Early receptor potential of a typical rod monochromat. Yonago Acta Med 18: 181–190
Walther G (1985) Des Frühe Rezeptorenpotential (ERP) und seine Anwendung in der Klinik. Dissertation, Augenklinik der Universität Hamburg
Yonemura, D, Kawasaki, K and Hasui, I (1966a) The early receptor potential in the human electroretinogram. Acta Soc Ophthalmol Jpn 70: 766–768
Yonemura, D, Kawasaki, K and Hasui, I (1966b) A new device with an automatic clamp of the starting point of sweep for clinical electroretinography. Acta Soc Ophthalmol Jpn 70: 2235–2237
Zanen, A and Debecker, J (1971) Visual pigments and melanin contributions to the fast photovoltage of the human eye. Vision Res 11: 169–172
Zanen, A and Debecker, J (1975) Wavelength sensitivity of the two components of the early receptor potential (ERP) of the human eye. Vision Res 15: 107–112
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Walther, G., Hellner, K.A. Early receptor potential recordings for clinical routine. Doc Ophthalmol 62, 31–39 (1986). https://doi.org/10.1007/BF00140544
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DOI: https://doi.org/10.1007/BF00140544