Skip to main content
Log in

Noninvasive method for estimating the mean capillary pressure and pre- and postcapillary resistance ratio in human fingers

  • Published:
Medical and Biological Engineering and Computing Aims and scope Submit manuscript

Abstract

A noninvasive method for estimating the mean capillary pressure Pcap and the pre-and postcapillary resistance ratio Rv/Ra in human fingers is described. Volume change in a finger segment was detected with a transmittance-type infra-red photoelectric plethysmograph during a gradual and linear increase in occluding cuff pressure. There was an inflection point in the volume curve which would be produced by the difference in the compliance between the arterial and venous vascular bed in the segment. This transitional point was assumed to represent the complete compression of the venous vascular bed at the cuff pressure level. Thus Pcap was defined as the cuff pressure corresponding to the inflection point. Rv/Ra was calculated from the Pcap, the venous pressure Pv and the mean arterial pressure Pam. The latter two pressures, Pv and Pam, were also indirectly and simultaneously measured by the compression pressure of another cuff and by our new type of volume oscillation method, respectively. The values of Pcap and Rv/Ra were in good agreement with those reported by other investigators.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Eichna, L. W. andBordley, J. III (1942) Capillary blood pressure in man. Direct measurements in the digits of normal and hypertensive subjects during vasoconstriction and vasodilatation variously induced.J. Clin. Invest.,21, 711–729.

    Article  Google Scholar 

  • Fahr, G. andErshler, I. (1941) Studies of the factors concerned in edema formation. II. The hydrostatic pressure in the capillaries during edema formation in right heart failure.Ann. Internal Med.,15, 798–810.

    Google Scholar 

  • Fronek, A. (1971) Isoconductometric estimation of effective capillary pressure in isolated hindlimb.Am. J. Physiol.,220, 1005–1008.

    Google Scholar 

  • Granger, D. N., Perry, M. A., Kvietys, P. R. andTaylor, A. E. (1983) A new method for estimating intestinal capillary pressure.,244, G341-G344.

    Google Scholar 

  • Hakim, T. S., Michel, R. P. andChang, H. K. (1982) Partitioning of pulmonary vascular resistance in dogs by arterial and venous occlusion.J. Appl. Physiol.,52, 710–715.

    Google Scholar 

  • Holloway, H., Perry, M., Downey, J., Parker, J. andTaylor, A. (1983) Estimation of effective pulmonary capillary pressure in intact lungs.J. Appl. Physiol.,54, 846–851.

    Google Scholar 

  • Johnson, P. C. (1965) Effect of venous pressure on mean capillary pressure and vascular resistance in the intestine.Circ. Res.,16, 294–300.

    Google Scholar 

  • Landis, E. M. (1926) The capillary pressure in frog mesentery as determined by micro-injection methods.Am. J. Physiol.,75, 548–570.

    Google Scholar 

  • Landis, E. M. (1930) Micro-injection studies of capillary blood pressure in human skin.Heart,15, 209–228.

    Google Scholar 

  • Landis, E. M. andPappenheimer, J. R. (1963) Exchange of substances through the capillary walls. InHandbook of physiology.Hamilton, W. F. andDow, P. (Eds), Am. Physiol. Soc., 961–1034.

  • Levick, J. R. andMichel, C. C. (1978) The effects of position and skin temperature on the capillary pressures in the fingers and toes.J. Physiol.,274, 97–109.

    Google Scholar 

  • MacLeod, M. (1960) Systemic capillary pressure, in acute glomerulonephritis estimated by direct micropuncture.Clin. Sci.,19, 27–33.

    Google Scholar 

  • Mahler, F., Muheim, M. H., Intaglietta, M., Bollinger, A. andAnliker, M. (1979) Blood pressure fluctuations in human nailfold capillaries.Am. J. Physiol.,236, H888-H893.

    Google Scholar 

  • Pappenheimer, J. R. andSoto-Rivera, A. (1948) Effective osmotic pressure of the plasma proteins and other quantities associated with the capillary circulation in the hindlimbs of cats and dogs.,152, 471–491.

    Google Scholar 

  • Penaz, J. (1973) Photoelectric measurement of blood pressure, volume and flow in the finger. Dig. 10th Int. Conf. Med. & Biol. Eng., Dresden, Session 7 Haemodynamics I, No. 7-2, 104.

    Google Scholar 

  • Rappaport, M. B., Bloch, E. H. andIrvin, J. W. (1959) A manometer for measuring dynamic pressures in the microvascular system.J. Appl. Physiol.,14, 651–655.

    Google Scholar 

  • Renkin, E. M. (1984) Control of microcirculation and bloodtissue exchange. InHandbook of physiology.Renkin, E. M., Michel, C. C. andGeiger, S. R. (Eds.), Am. Physiol. Soc., 627–687.

  • Roy, C. S. andBrown, J. G. (1880) The blood-pressure and its variations in the arterioles, capillaries and smaller veins.J. Physiol.,2, 323–359.

    Google Scholar 

  • Shimazu, H., Fukuoka, M., Hayashi, S., Seki, K., Ito, H., Yamakoshi, K. andTogawa, T. (1985) Noninvasive measurement of pressure/volume characteristics in human limb veins by electrical admittance plethysmography.Med. & Biol. Eng. & Comput.,23, 38–42.

    Google Scholar 

  • Von Kries, N. (1875) Ueber den Druck in den Blutcapillaren der menschlichen Haut.Arbeiten Physiol., Anstalt Leipzig,10, 69–80.

    Google Scholar 

  • Wiederhielm, C. A., Woodbury, J. W., Kirk, S. andRushmer, R. F. (1964) Pulsatile pressures in the microcirculation of frog's mesentery.Am. J. Physiol.,207, 173–176.

    Google Scholar 

  • Yamakoshi, K., Shimazu, H. andTogawa, T. (1979) Indirect measurement of instantaneous arterial blood pressure in the rat.Am. J. Physiol.,237, H632-H637.

    Google Scholar 

  • Yamakoshi, K., Shimazu, H. andTogawa, T. (1980) Indirect measurement of instantaneous arterial blood pressure in the human finger by the vascular unloading technique.IEEE Trans.,BME-27, 150–155.

    Google Scholar 

  • Yamakoshi, K., Shimazu, H., Shibata, M. andKamiya, A. (1982a) New oscillometric method for indirect measurement of systolic and mean arterial pressure in the human finger. Part 1: model experiment.Med. & Biol. eng. & Comput.,20, 307–313.

    Article  Google Scholar 

  • Yamakoshi, K., Shimazu, H., Shibata, M. andKamiya, A. (1982b) New oscillometric method for indirect measurement of systelic and mean orterial pressure in the human finger. Part 2: correlation study,20, 314–318.

    Article  Google Scholar 

  • Zweifach, B. W. (1956) Rat mesoappendix procedure for bioassay of humoral substances acting on peripheral blood vessels.Ergeb. Anat. Entwicklngsgesch.,35, 175–186.

    Google Scholar 

  • Zweifach, B. W. (1974) Quantitative studies of microcirculatory structure and function. II. Direct measurement of capillary pressure in splanchinic mesenteric vessels.Circ. Res.,34, 858–867.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shimazu, H., Ito, H. & Yamakoshi, K. Noninvasive method for estimating the mean capillary pressure and pre- and postcapillary resistance ratio in human fingers. Med. Biol. Eng. Comput. 24, 585–590 (1986). https://doi.org/10.1007/BF02446260

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02446260

Keywords

Navigation