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Occurrence of campylobacter pyloridis in patients from Vienna with gastritis and peptic ulcers

Das Vorkommen von Campylobacter pyloridis bei Patienten mit Gastritis und peptischem Ulkus in Wien

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Summary

During routine gastroduodenoscopic examination of 120 patients, biopsies of gastric mucosa were taken for the isolation ofCampylobacter pyloridis. The organism was isolated from six of seven patients with ulcus ventriculi, 14 of 15 with ulcus duodeni, 15 of 20 with erosions of the gastric mucosa, 31 of 61 with gastritis and five of five with duodenitis. In contrast, the cultures were negative in all of the 12 patients with histologically normal mucosa.C. pyloridis was isolated significantly more frequently from patients with active chronic gastritis than from those with inactive chronic gastritis (100% vs. 50%). These results support the suggestion ofMarshall andWarren that this bacterium may play an important role in the development of gastritis and peptic ulcer.

Zusammenfassung

Bei insgesamt 120 Patienten wurden im Rahmen routinemäßiger gastroduodenoskopischer Untersuchungen Schleimhautbiopsien zur Kultivierung vonCampylobacter pyloridis entnommen. Bei sechs von sieben Patienten mit Ulcus ventriculi, 14 von 15 mit Ulcus duodeni, 15 von 20 mit Erosionen der Magenschleimhaut, 31 von 61 mit Gastritis und fünf von fünf mit Duodenitis konnteC. pyloridis isoliert werden. Hingegen war der Keimnachweis bei allen 12 Patienten mit histologisch unauffälliger Mukosa nicht möglich. Bei chronisch aktiver Gastritis ließ sichC. pyloridis signifikant häufiger als bei chronisch inaktiver Gastritis nachweisen (100 bzw. 50%). Diese Ergebnisse stützen die Hypothese vonMarshall undWarren, die besagt, daßC. pyloridis möglicherweise eine wichtige Rolle in der Entstehung von Gastritis und Ulcus pepticum zukommt.

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Authors and Affiliations

  1. Hygiene Institute, University of Vienna, Kinderspitalgasse 15, A-1095, Vienna

    A. Hirschl,  G. Stanek, Linda Wende &  M. Rotter

  2. 1st. Department of Gastroenterology and Hepatology, University of Vienna, Lazarettgasse 14, A-1090, Vienna

    Regina Pötzi &  A. Gangl

  3. Institute of Pathological Anatomy, University of Vienna, Spitalgasse 4, A-1090, Vienna

    J. H. Holzner

Authors
  1. A. Hirschl
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  2. G. Stanek
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  3. Linda Wende
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  4. M. Rotter
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  5. Regina Pötzi
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  6. A. Gangl
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  7. J. H. Holzner
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Hirschl, A., Stanek, G., Wende, L. et al. Occurrence of campylobacter pyloridis in patients from Vienna with gastritis and peptic ulcers. Infection 14, 275–278 (1986). https://doi.org/10.1007/BF01643961

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  • DOI: https://doi.org/10.1007/BF01643961

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