Abstract
A case of a 33-year-old pentazocine-addicted man (450 mg daily) is described. Histochemical and quantitative histographic analyses of the muscle biopsy disclosed type 2 atrophy.
We consider that this indicates that there is a generalized toxic effect of pentazocine.
Sommario
Viene descritto un caso di abuso di pentazocine (450 mg die) in un uomo di 33 a. Lo studio bioptico muscolare dal punto di vista istochimico e istografico quantitativo ha dimostrato una atrofia delle fibre del tipo 2. Si suggerisce la possibilità di un danno tossico generalizzato da parte della pentazocina.
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References
Burnam H. A.:Pentazocine-induced fibrous myopathy. J.A.M.A., 234: 913, 1975.
Dubowitz V., Brooke M. H.:Muscle biopsy: a modern approach. Saunders, 1973.
Fleiss D.:Pentazocine-induced fibrous myopathy. J.A.M.A., 232: 1128, 1975.
Levin B. E., Engel W. K.:Iatrogenic muscle fibrosis. J.A.M.A., 234: 622–624, 1975.
Oh S. J.:Experimental pentazocine-induced fibrous myopathy. Alab. J. Med. Sci., 14: 64–67, 1977.
Parks D. L., Perry H. O., Muller S. A.:Cutaneous complications of pentazocine injections. Arch. Derm., 104: 231–235, 1971.
Schlicher J. E., Zuelcke R. L., Lynch P. J.:Local changes at the site of pentazocine injection. Arch. Derm., 104: 90–91, 1971.
Swanson D. W., Weddige R. L., Morse R. M.:Hospitalized pentazocine abusers. Mayo Clin. Proc., 48: 83–93, 1973.
Steiner J. C., Winkelman A. C., de Jesus P. V.:Pentazocine-induced myopathy. Arch. Neurol., 28: 408–409, 1973.
Winfield J. B., Greer K.:Cutaneous complications of parenterally administered pentazocine. J.A.M.A., 225: 189–190, 1973.
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Mariani, C., Albizzati, M.G., Boni, S. et al. Type 2 atrophy in a pentazocine addicted patient. Ital J Neuro Sci 1, 113–118 (1979). https://doi.org/10.1007/BF02336853
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DOI: https://doi.org/10.1007/BF02336853