Summary
Both the presence of sodium and of an electrical potential difference across the membrane have been found to be necessary in order to achieve optimald-glucose-protectable phlorizin binding to brush border membranes from rabbit small intestine. The effect of\(\Delta \tilde \mu _{Na} \) on phlorizin binding shows a close similarity to that ond-glucose transport, confirming that phlorizin is indeed bound to thed-glucose transporting protein. Possible modulations of binding by a transmembrane potential are discussed on the basis of some models.
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Toggenburger, G., Kessler, M., Rothstein, A. et al. Similarity in effects of Na+ gradients and membrane potentials ond-glucose transport by, and phlorizin binding to, vesicles derived from brush borders of rabbit intestinal mucosal cells. J. Membrain Biol. 40, 269–290 (1978). https://doi.org/10.1007/BF02002972
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DOI: https://doi.org/10.1007/BF02002972