Summary
Thirty-six patients undergoing Dimer X or Amipaque ventriculography or myelography underwent electroencephalographic investigations. In most cases EEG alterations were found. They ranged from general slowing to seizure potentials. These findings and their causes are discussed.
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References
Agnoli, A., Eggert, H. R., Zierski, J., Seeger, W., Kirchhoff, D., Diagnostische Möglichkeiten der positiven Ventrikulographie. Acta neurochir. (Wien)31 (1975), 227–243.
Allen, W. E., Van Gilder, J. C., Collins, W. F., Evaluation of the neurotoxicity of water-soluble myelographic contrast agents by electrophysiological monitors. Radiology118 (1976), 89–95.
Andriolo, G. C., Galligioni, F., Marin, G., Salar, G., Further observations on ventriculography with watersoluble contrast medium. J. Neurosurg. Sci.17 (1973), 167–177.
Bagchi, A. K., Convulsions, subarachnoid haemorrhage and death following myelography with meglumine iothalamate. Surg. Neurol.5 (1976), 285–286.
Clar, H. E., Bock, W. J., Fiebach, O., Vergleich positiver und negativer Kontrastmittel zur Darstellung des 3. und 4. Ventrikels. Fortschr. Röntgenstr.121 (2) (1974), 153–158.
Corrales, M., Tapia, J., Encephalography with metrizamide. Neuroradiology13 (1977), 249–254.
Drayer, B. P., Rosenbaum, A. E., Metrizamide brain penetrance. Acta Radiol. (Stockh.) Suppl.355 (197), 280–293.
Elies, W., Todorow, S., Beobachtungen über den Resorptionsweg eines öligen Kontrastmittels (Duroliopaque) nach spinaler Myelographie. Fortschr. Röntgenstr.120 (5) (1974), 603–608.
Finck, M., Vogelsang, H., Experience with Dimer X-ventriculography. Neuropäd.6 (1975), 339–346.
Fischer, D. E., Neurotoxicität von Röntgenkontrastmitteln. Radiologe10 (12) (1970), 485–488.
Gonsette, R., An experimental and clinical assessment of water-soluble contrast medium in neuroradiology. A new medium-Dimer X. Clin. Radiol.22 (1) (1971), 44–56.
Gonsette, R. E., Biologic tolerance of the central nervous system to metrizamide. Acta Radiol.(Stockh.) Suppl.335 (1973), 25–44.
Gonsette, R. E., Metrizamide as contrast medium for myelography and ventriculography. Acta Radiol. (Stockh.) Suppl.335 (1973), 346–358.
Gonsette, R., André-Balisaux, G., Etude expérimentale et clinique de quelques produits de contraste hydrosolubles en vue de leur utilisation pour la radiculographie, la myélographie et la ventriculographie. J. Radiol. Électrol.51 (1–2) (1970), 19–28.
Gonsette, R. E., Brucher, J. M., Potentiation of amipaque epileptogenic activity by neuroleptics. Neuroradiology14 (1977), 27–30.
Grepe, A., Widén, L., Neurotoxic effect of intracranial subarachnoid application of metrizamide and meglumine iocarmate. An experimental investigation in dogs in neurolept analgesia. Acta Radiol. (Stockh.) Suppl.335 (1973), 102–118.
Grepe, A., Widen, L., Effects of cisternal application of metrizamide. Acta Radiol. (Stockh.) Suppl.335 (1973), 119–124.
Guthkelch, A. V., Zierski, J., Fernandes-Serrats, A. A., Chatterjee, S. P., Ventriculography with meglumine iothalamate. Neuroradiology6 (1971), 32–38.
Hansen, E. B., Fahrenkrug, A., Praestholm, J., Late meningeal effects of myelographic contrast media with special reference to metrizamide. Brit. J. Radiol.51 (1978), 321–327.
Heimburger, R. F., Kaisbeck, J. E., Campbell, R. L., Mealey, J., Positive contrast cerebral ventriculography using water-soluble media. J. Neurol. Neurosurg. Psychiat.29 (1966), 281–289.
Hindmarsh, T., Methiodal sodium and metrizamide in lumbar myelography. Acta Radiol. (Stockh.) Suppl.335 (1973), 359–366.
Hindmarsh, J., Lumbar myelography with meglumine iocarmate and metrizamide. Acta Radiol.(Stockh.) Diagnosis16 (1975), 209–222.
Hindmarsh, T., Grepe, A., Widén, L., Metrizamide—phenothiazine interaction. Acta Radiol. (Stockh.) Diagnosis16 (1975), 129–134.
Irstam, L., Side effects of water-soluble contrast media in lumbar myelography. Acta Radiol. (Stockh.)14 (1973), 647–656.
Irstam, L., Sellden, U., Side effects after lumbar myelography with dimeglumine iocarmate (Dimer X). Acta Radiol. (Stockh.) Diagnosis16 (1975), 449–462.
Irstam, L., Sellden, U., Adverse effects of lumbar myelography with Amipaque and Dimer X. Acta Radiol. (Stockh.) Diagnosis17 (1976), 145–159.
Kaada, B., Transient EEG abnormalities following lumbar myelography with metrizamide. Acta Radiol. (Stockh.) Suppl.335 (1973), 380–386.
Kandel, E. I., Combined Conray-Myodil ventriculography. Acta neurochir. (Wien)40 (1978), 151–156.
Kunze, St., Wasserlösliche Kontrastmittel bei Tumoren des Spinalkanals unter besonderer Berücksichtigung der Komplikationen. In: Spinale raumfordernde Prozesse, S. 145–150 (Schiefer, W., Wieck, H. H., eds). Erlangen: Dr. D. Straube. 1976.
Kunze, St., Klinger, M., Schiefer, W., Central ventriculography with Dimer X. Acta neurochir. (Wien)28 (1973), 41–63.
Kunze, St., Schiefer, W., Die Verwendung wasserlöslicher resorbierbarer Kontrastmittel zur zentralen Ventrikulographie und Myelographie — Indikation, Technik, Ergebnisse und Komplikationen. Zbl. Neurochir.25 (1) (1974), 1–19.
Laasonen, E. M., Ehrström, J., Toivakka, E., Ronkkala, M., Die Nebenwirkungen von Metrizamid und Meglumin-Iocarmat bei der lumbalen Myelographie. Fortschr. Röntgenstr.127 (5) (1977), 483–486.
Mohadjer, M., Hänsel, G., Vergleich der wässerigen Kontrastmittel Conray 60 und Dimer X zur Darstellung des Hirnventrikelsystems. Neurochirurgia17 (1974), 11–16.
Natelson, S. E., Sayers, M. P., Hunt, W. E., Experiences with the technique and complications of meglumine iothalamate (Conray) ventriculography. J. Neurol. Neurosurg. Psychiat.35 (1972), 264–269.
Nielsen, H., Epileptic seizures following cervical myelography. Neuroradiology10 (1975), 59–60.
Oftedal, S.-J., Intraventricular application of water-soluble contrast media in cats. Acta Radiol. (Stockh.) Suppl.335 (1973), 125–132.
Oftedal, S.-J., Kayed, K., Epileptogenic effect of water-soluble contrast media. Acta Radiol. (Stockh.) Suppl.335 (1973), 45–56.
Oftedal, S.-J., Sawhney, B. B., Effect of water-soluble contrast media on cortically evoked potentials in the cat. Acta Radiol. (Stockh.) Suppl.335 (1973), 133–142.
Picaza, J. A., Hunter, S. E., Lee, L., Seizures associated with the use of meglumine iothalamate 60% in ventriculography. J. Neurosurg.36 (1972), 474–480.
Prange, H., Poser, S., Cerebrale Krampfanfälle nach lumbaler Dimer-X-Myelographie (weitere Fallberichte). Nervenarzt48 1977, 433–436.
Rapoport, St. J., Levitan, H., Neurotoxicity of X-ray contrast media. Amer. J. Roentgenol.122 (1) (1974), 186–193.
Ropper, A. H., Chiappa, K., Young, R. R., The effect of metrizamide on the EEG: A prospective study in 62 cases. Trans. Amer. neurol. Ass.103 (1978), 159–162.
Schmidt, R. C., Mental disorders after myelography with metrizamide and the water-soluble contrast media. Neuroradiology19 (1980), 153–157.
Skalpe, J. O., Torbergsen, T., Amundsen, P., Presthus, J., Lumbar myelography with metrizamide. Acta Radiol. (Stockh.) Suppl.335 (1973), 367–379.
Speck, U., Schmidt, R., Volkhardt, V., Vogelsang, H., The effect of position of patient on the passage of metrizamide (Amipaque), meglumine iocarmate (Dimer X) and ioserinate (Myelografin) into the blood after lumbar myelography. Neuroradiology14 (1978), 251–256.
Suzuki, S., Kawaguchi, S., Mita, R., Iwabuchi, F., Ventriculography with methylglucamine iocarmate (Dimer X). Experimental and clinical study. Acta neurochir. (Wien)33 (1976), 219–231.
Svare, A., Talle, K., Lumbar myelography with metrizamide. Acta Radiol. (Stockh.) Suppl.335 (1973), 387–390.
Thomas, L. B., Foltz, E. L., Ward, A. A., The modification of cerebral electrical activity by intracarotid and topically applied diodrast. Electroenceph. Clin. Neurophysiol.6 (1954), 643–652.
Vogelsang, H., Diskussionsbeitrag zur Arbeit von H. Prange und S. Poser: „Cerebrale Krampfanfälle nach lumbaler Dimer-X-Myelographie“. Nervenarzt49 (1978), 65–66.
Vogelsang, H., Schmidt, R. E., Spinale Reizerscheinungen nach Myelographien mit Amipaque bei Patienten mit schweren Kyphoskoliosen. Fortschr. Röntgenstr.131 (1) (1979), 90–92.
Vogelsang, H., Schmidt, R., Busse, O., Dangel, U., Myelographie mit Metrizamide (Amipaque). Acta neurochir. (Wien)40 (1978), 157–173.
Walker, N., Egli, M., Wellauer, J., Nebenreaktionen nach lumbaler Myelographie mit Dimer X. Z. Orthop.114 (1976), 793–804.
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Nau, H.E. Electroencephalography (EEG) after introduction of water soluble contrast media into cerebrospinal fluid (CSF). Acta neurochir 57, 75–82 (1981). https://doi.org/10.1007/BF01665116
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DOI: https://doi.org/10.1007/BF01665116