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Eosinophils as host cells for HIV-1

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Summary

Transient expression of HIV-1 p24 antigen was observed in eosinophils acutely infected with the HTLV-IIIB strain of HIV-1. PCR analysis of eosinophils isolated from 18 seropositive individuals showed HIV-1 sequences to be present in 2 subjects. These data suggest that eosinophils may act as host cells for HIV-1.

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Authors and Affiliations

  1. Infectious Diseases Unit, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA

    B. Conway, L. J. Bechtel, Joan C. Kaplan & M. S. Hirsch

  2. Division of Infectious Diseases, Ottawa General Hospital, Ottawa, Ontario, Canada

    B. Conway

  3. Department of Dermatology, State University of New York at Buffalo, Buffalo, New York

    P. Baskar & Stephanie H. Pincus

  4. Division of Infectious Diseases, University of Colorado, Denver, Colorado, USA

    R. T. Schooley

Authors
  1. B. Conway
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  2. P. Baskar
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  3. L. J. Bechtel
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  4. Joan C. Kaplan
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  5. M. S. Hirsch
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  6. R. T. Schooley
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  7. Stephanie H. Pincus
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Conway, B., Baskar, P., Bechtel, L.J. et al. Eosinophils as host cells for HIV-1. Archives of Virology 127, 373–377 (1992). https://doi.org/10.1007/BF01309600

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  • DOI: https://doi.org/10.1007/BF01309600

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