Skip to main content
SpringerLink
Log in

In-vivo studies on C2 organic acids in the tissues of rats injected with xylitol and glucose

  • Original Contributions
  • Published:
Zeitschrift für Ernährungswissenschaft Aims and scope Submit manuscript

Summary

Oxalic, glyoxylic, and glycollic acid were determined in rat liver and kidney after injection with [U-14C]-xylitol or [U-14C]-glucose. Neither glucose nor xylitol led to the formation of oxalic and glyoxylic acid, yet glycollic acid was found in both tissues after injection with xylitol.

Possible pathways leading from xylitol to glycollic acid are discussed.

Zusammenfassung

Oxal-, Glyoxyl- und GlykollsÄure wurden in Rattenleber und -niere nach Injektion von [U-14C]-Xylit oder [U-14C]-Glucose bestimmt. Weder Glucose noch Xylit führten zu einer Oxal- oder GlyoxylsÄurebildung. GlycollsÄure wurde jedoch in beiden Geweben nach Injektion von Xylit gefunden.

Mögliche Stoffwechselwege vom Xylit zur GlykollsÄure werden diskutiert.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Watts, R. W. E., J. Roy. Coll. Physcns. Lon.,7, 161 (1973).

    CAS  Google Scholar 

  2. Williams, H. E., and L. H. Smith Jr., Amer. J. Med.45, 715 (1968).

    Article  CAS  Google Scholar 

  3. Thomas, D. W., J. B. Edwards, J. E. Gilligan, J. R. Laurence, and R. G. Edwards, Med. J. Australia3, 1238 (1972).

    Google Scholar 

  4. Schröder, R., W. F. De Lacroix, J. Franzen, P. J. Klein, and W. Müller, Acta Neuropathol.,27, 181 (1974).

    Article  Google Scholar 

  5. Hauschildt, S., R. A. Chalmers, A. M. Lawson, K. Schulthis, and R. W. E. Watts, Amer. J. Clin. Nutr.29, 258 (1976).

    CAS  Google Scholar 

  6. Dean, B. M., R. W. E. Watts, W. J. Westwick, Clin. Sci.35, 325 (1968).

    CAS  Google Scholar 

  7. Katz, J., K. Brand, S. Goldberg, and D. Rubinstein, Cancer Res.34, 872 (1974).

    CAS  Google Scholar 

  8. Good, C. A., H. Kramer, and M. Somogyi, J. Biol. Chem.100, 485 (1933).

    CAS  Google Scholar 

  9. Maurer, C., and P. Christophus, Z. Klin. Chem. Klin. Biochem.,11, 535 (1973).

    CAS  Google Scholar 

  10. Chalmers, R. A., and R. W. E. Watts, Analyst. (Lond.),97, 958 (1972).

    Article  CAS  Google Scholar 

  11. Mayer, G., D. Markow, and F. Karp, Clin. Chem.,9, 334 (1963).

    CAS  Google Scholar 

  12. Hagler, L., and R. H. Herman, Amer. J. Clin. Nutr.26, 758 (1973).

    CAS  Google Scholar 

  13. Müller, F., E. Strack, E. Kuhfahl, and D. Dettmer, Z. Ges. Exp. Med.,142, 338 (1967).

    Article  Google Scholar 

  14. BÄssler, K. H., G. Stein, and W. Belzer, Biochem. Z.346, 171 (1966).

    Google Scholar 

  15. Quadflieg, K. H., and K. Brand, Z. ErnÄhrungswiss.,15, 346 (1976).

    Article  Google Scholar 

  16. Asami, S., and T. Akazawa, Plant and Cell Physiol.,16, 805 (1975).

    CAS  Google Scholar 

  17. Oshinsky, R. J., Y. M. Wang, and J. Van Eys, J. Nutr.107, 792 (1977).

    CAS  Google Scholar 

Download references

Author information

Author notes

  1. S. Hauschildt

    Present address: Physiologisches-Chemisches Institut der UniversitÄt Erlangen-Nürnberg, Erlangen, FRG

Authors and Affiliations

  1. Physiologisches-Chemisches Institut der UniversitÄt Erlangen-Nürnberg, Erlangen, FRG

    K. Brand

  2. Division of Inherited Metabolic Diseases, The M.R.C. Clinical Research Centre, HA1 3VJ, Harrow, Middlesex, UK

    R. A. Chalmers

  3. Division of Clinical Chemistry, The M.R.C. Clinical Research Centre, HA1 3VJ, Harrow, Middlesex, UK

    A. M. Lawson

Authors
  1. S. Hauschildt
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. A. Chalmers
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. M. Lawson
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. K. Brand
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hauschildt, S., Chalmers, R.A., Lawson, A.M. et al. In-vivo studies on C2 organic acids in the tissues of rats injected with xylitol and glucose. Z Ernährungswiss 20, 69–75 (1981). https://doi.org/10.1007/BF02027959

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02027959

Search

Navigation