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New Programs for Protein Tertiary Structure Prediction

Bio/Technology volume 11, pages 479–484 (1993)Cite this article

Abstract

Prediction of protein tertiary structure remains an unsolved problem in molecular biology, but a solution to this problem is extremely important for protein engineering and rational drug design. Recent developments in motif recognition and side chain modeling present the prospect of nearly automatic model building for a large fraction of newly determined protein sequences. We review some of these new algorithms and present preliminary results of their application to the prediction of a structure for fasciclin III, a neural adhesion molecule from Drosophila.

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  1. Jacquelyn S. Fetrow: Corresponding author

Authors and Affiliations

  1. Department of Biological Sciences, University at Albany, SUNY, 1400 Washington Avenue, Albany, NY, 12222

    Jacquelyn S. Fetrow

  2. National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, 8600 Rockville Pike, Bethesda, MD, 20894

    Stephen H. Bryant

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  1. Jacquelyn S. Fetrow
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  2. Stephen H. Bryant
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Fetrow, J., Bryant, S. New Programs for Protein Tertiary Structure Prediction. Nat Biotechnol 11, 479–484 (1993). https://doi.org/10.1038/nbt0493-479

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