Abstract
THE anticipation of movement might increase blood flow to the skeletal muscles, and it is usually assumed that this adaptive function is performed by the sympathetic cholinergic system1. This consists of a series of cerebral relays connecting the motor cortex, the hypothalamus, and the mesencephalic periaqueductal grey to sympathetic postganglionic neurones exerting an atropine-sensitive dilating action on the vasculature of skeletal muscles2,3. Although it has been demonstrated that the sympathetic cholinergic system can be conditioned4,5, there is no clear evidence of its relationship to movement, nor any basis for suggesting that its function is specific, limited to active muscles (as would be expected should it subserve muscle exercise2), or more diffuse and indiscriminate (as might be advantageous in emotional behaviour6). The study described here was designed to define more precisely whether the sympathetic cholinergic system can exert a specific and motor-related action.
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References
Uvnäs, B., Handbook of Physiology, Section 1, Neurophysiology, 2, 1131 (Amer. Physiol. Soc., Washington, 1960).
Eliasson, S., Folkow, B., Lindgren, P., and Uvnäs, B., Acta Physiol. Scand., 23, 333 (1951).
Lindgren, P., Acta Physiol. Scand., Suppl., 35, 121 (1955).
Abrahams, V. C., Hilton, S. M., and Zbrožyna, A., J. Physiol., 171, 189 (1964).
Bolme, P., and Novotny, J., Acta Physiol. Scand., 77, 58 (1969).
Abrahams, V. C., Hilton, S. M., and Zbrožyna, A., J. Physiol., 154, 491 (1960).
Snedecor, G. W., and Cochran, W. G., Statistical Methods (Iowa State University Press, Ames, 1967).
Herz, A., Teschemacher, H., Hofstetter, A., and Kurz, H., Intern. J. Neuropharmacol., 4, 207 (1965).
Guazzi, M., Mancia, G., Kumazawa, T., Baccelli, G., and Zanchetti, A., Cardiovascular Res., 3, 265 (1968).
Adams, D. B., Baccelli, G., Mancia, G., and Zanchetti, A., Nature, 220, 1239 (1968).
Miller, N. E., Science, 163, 434 (1969).
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ELLISON, G., ZANCHETTI, A. Specific Appearance of Sympathetic Cholinergic Vasodilatation in Muscles during Conditioned Movements. Nature 232, 124–125 (1971). https://doi.org/10.1038/232124a0
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DOI: https://doi.org/10.1038/232124a0
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