Abstract
λ phage with amber mutations in the N gene can persist indefinitely as an independent replicating unit, a plasmid, in the cytoplasm of host E. coli cells. This newly discovered mode of λ phage lysogeny may shed light on the evolution of plasmids and temperate phage.
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SIGNER, E. Plasmid Formation: a New Mode of Lysogeny by Phase λ. Nature 223, 158–160 (1969). https://doi.org/10.1038/223158a0
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DOI: https://doi.org/10.1038/223158a0
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