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Electron Microscopy of Monkey Kidney Cells infected with both SV40 and Measles Virus

Abstract

THE ultrastructure of cells infected with SV40 alone has been described previously by several investigators1–4. The morphology of the internal component of measles virus in infected cells has also been described5–7. Single cells infected with these two viruses have not been reported, however. In a previous study, a mixed infection with both SV40 and measles virus was obtained in a lot of cell cultures prepared from the kidney of a sick green monkey8. Mixed infection with these two viruses was later experimentally induced in tissue culture, and doubly infected cells were noted on examination by light microscopy9. The present communication describes the electron microscopy of cells in cultures doubly infected with SV40 and measles virus, and observation of the fine structure of both viruses in the same nucleus.

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References

  1. Gaylord, W. H., and Hsiung, G. D., J. Exp. Med., 114, 987 (1961).

    Article  Google Scholar 

  2. Tournier, P., Granboulan, N., and Bernhard, W., C.R. Acad. Sci., Paris, 253, 2283 (1961).

    CAS  Google Scholar 

  3. Easton, J. M., Proc. Soc. Exp. Biol. and Med., 114, 663 (1963).

    Article  CAS  Google Scholar 

  4. Shestopalova, N. M., Reingold, V. N., Kolyaskina, G. L., and Chumakov, M. P., Fed. Proc., 23, 855 (1964).

    CAS  Google Scholar 

  5. Baker, R. F., Gordon, I., and Rapp, F., Nature, 185, 790 (1960).

    Article  ADS  CAS  Google Scholar 

  6. Tawara, T., Virology, 25, 322 (1965).

    Article  CAS  Google Scholar 

  7. Norrby, E., and Magnusson, P., Archiv. Virusforschung, 17, 443 (1965).

    Article  CAS  Google Scholar 

  8. Hsiung, G. D., and Atoynatan, T., J. Epidemiol., 83, 38 (1966).

    Article  CAS  Google Scholar 

  9. Hsiung, G. D., Atoynatan, T., and Gluck, L., Proc. Soc. Exp. Biol. and Med., 121, 562 (1966).

    Article  CAS  Google Scholar 

  10. Prose, P. H., Balk, S. D., Liebhaber, H., and Krugman, S., J. Exp. Med., 122, 1151 (1965).

    Article  CAS  Google Scholar 

  11. Compans, R. W., Holmes, K. V., Dales, S., and Choppin, P. W., Virology, 30, 411 (1966).

    Article  CAS  Google Scholar 

  12. Granboulan, P., Tournier, P., Wicker, R., and Bernhard, W., J. Cell Biol., 17, 423 (1963).

    Article  CAS  Google Scholar 

  13. O'Conor, G. T., Rabson, A. S., Berezesky, I. K., and Paul, F. J., J. Nat. Cancer Inst., 31, 903 (1963).

    CAS  PubMed  Google Scholar 

  14. Rabson, A. S., O'Conor, G. T., Paul, F. J., and Berezesky, I. K., Science, 151, 1535 (1966).

    Article  ADS  CAS  Google Scholar 

  15. Rowe, W. P., and Baum, S. G., Proc. US Nat. Acad. Sci., 52, 1340 (1964).

    Article  ADS  CAS  Google Scholar 

  16. Rapp, F., Melnick, J. L., Butel, J. S., and Kitahara, T., Proc. US Nat. Acad. Sci., 52, 1348 (1964).

    Article  ADS  CAS  Google Scholar 

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HSIUNG, G., BENSCH, K. & PROSE, P. Electron Microscopy of Monkey Kidney Cells infected with both SV40 and Measles Virus. Nature 215, 178–179 (1967). https://doi.org/10.1038/215178a0

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